Flashcards in Baker: Membrane Transport Deck (16):
What is the structure of a glycerophospholipid?
Glycerol linker attached to two fatty acid chains and a phosphate- alcohol complex.
What are the two possible structures of a sphingolipid
sphingosine attached to a fatty acid and either a phosphate-alcohol complex or a sugar.
What is the structure of a Cholesterol?
A Sterane linker attached to a hydroxyl group and an aliphathic chain
what affects the rate of diffusion across a membrane?
Size and charge of the molecule.
What are the two molecules we discussed that are permeable across a membrane? What are the two that are not permeable?
In order of most permeable to least permeable:1. Hydrophobic molecules (O2, CO2, N2)2. Small, uncharged polar molecules (H20, Glycerol)3. Large, uncharged polar molecules (Glucose, sucrose)4. Ions
What are the 4 types of membrane proteins and what is their general description?
1. Integral membrane proteins - stuck completely through the membrane and out both sides.2. Peripheral membrane proteins - stuck to just one side of the membrane.3. Associated membrane protein - influences membrane, but not directly attached. They are attached through another protein.4. Anchor membrane protein - a protein anchored into the membrane.
Which proteins can be easily removed from the membrane?
Peripheral and anchor proteins
Do all membranes have the same composition of proteins?
No, all have a different amount of different types, even organelles have different types.
In an integral membrane protein, which types of amino acids would be on the outside of the cell membrane? Which types would be on the inside?
Hydrophilic amino acids (non polar) would be on the outside, while hydrophobic (polar) would be on the inside.
How does a membrane in cold temperatures differ from a membrane at high temperatures?
A low temperature membrane would be composed of more unsaturated fatty acids, while the higher temperature would be composed of more saturated fatty acids.
What are the catalysts to move a lipid across a membrane?
Flippase, Floppase, Scramblase
Can proteins be moved across a membrane?
What are the 6 ways to move a solute across a membrane?
1. Simple diffusion2. Facilitated diffusion3. Primary active transport4. Secondary active transport5. Ion channel6. Ionophore mediated ion transport
What is ionophore mediated ion transport?
Basically an ion gets encompassed inside of a small molecule that can diffuse across a membrane.
What are the 3 different protein channels that can transport solutes across a membrane?
1. Uniport2. Symport3. Antiport