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Flashcards in Basics of Drugs Deck (33):
1

Endogenous Catecholamines

Epinephrine: a1, a2, B1, B2
Norepinephrine: a1, a2, B1
Dopamine: D1, B1, a1

2

Epinephrine

a1, a2, B1, B2

3

Norepinephrine

a1, a2, B1

4

Dopamine

D1, B1, a1

5

Nonselective B Receptor Agonist

Isoproterenol: B1, B2
Dobutamine: B1

6

Isoproterenol

B1, B2

7

Dobutamine

B1

8

B2 Selective Agonists

Albuterol: B2
Salmeterol: B2

9

a1 Selective Agonist

Phenylephrine: a1

10

Phenylephrine

a1

11

a2 Selectie Agonists

Clonidine: a2
Methyldopa: a2

12

Miscellaneous Sympathomimetics:

Tyramine
Amphetamine
Pseudophedrine

13

Tyramine

Release NE from sympathetic nerves

14

Amphetamine

Release NE from sympathetic nerves

15

Pseudoephedrine

Direct a1 agonist
Slight B1 agonist

16

Adrenergic Neuron Blockers

Guanethidine: Replace NE in vesicles after taken up by NET

Guanadrel: Replace NE in vesicles after taken up by NET

Resperine: Inhibits VMAT2

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Guanethidine:

Replace NE in vesicles after taken up by NET

18

Guanadrel

Replace NE in vesicles after taken up by NET

19

Resperine

Inhibits VMAT2 (VMAT2 is what lets Dopamine into the vessel to be turned into NE with RLS being Tyrosine hydroxylase)

20

Non-Selective a Antagonists

Phentolamine: a1, a2 (reversible)
Phenoxybenzamine: a1, a2 (permanent)

21

Phentolamine

a1, a2 (reversible) antagonist

22

Phenoxybenzamine:

a1, a2 (permanent) antagonist

23

Non-selective B Antagonists

Propranolol: B1, B2
Timolol: B1, B2

24

Propranolol:

B1, B2 antagonist

25

Timolol

B1, B2 antagonist

26

B1-Selective Antagonists

Metoprolol: B1 antagonist
Atenolol: 1 (no CNS)

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Metoprolol

B1 antagonist

28

Atenolol:

B1 (no CNS) antagonist

29

B Antagonists w/ additional CV actions

Labetolol: a1, B1, B2 antagonist
Carvedilol: a1, B1, B2 antagonist

30

Labetolol:

a1, B1, B2 antagonist

31

Carvedilol:

a1, B1, B2 antagonist

32

Albuterol:

B2 agonist

33

Salmeterol

B2 agonist