BB LAB - Glossary II Flashcards Preview

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Flashcards in BB LAB - Glossary II Deck (60):
1

fusion of malignant and normal cell that produces large quantities of monoclonal antibodies

murine hybridoma

2

group of sugars found on rbc membrane attached to a protein backbone

NANA (Sialic acid)

3

major source of membrane's net negative charge

NANA (Sialic acid)

4

relating to birth

natal

5

before birth

prenatal

6

after birth

postnatal

7

newborn infant up to 4 months of age

neonate

8

enzyme that cleaves sialic acid from rbc membrane

neuraminidase

9

also known as agglutination-inhibition

Neutralization

10

refers to absence of agglutination due to inability of an Ab to react with red cell antigen because of previously bound soluble substance

Neutralization

11

principle involved in saliva testing

Neutralization

12

basic building blocks of DNA composed of phosphate group, sugar group and base

nucleotide

13

any individual who fails to express any antigens on red cells

null phenotype

14

chemical compound formed by a small number of simple carbohydrate molecules

oligosaccharide chain

15

required temp in C by which the antibody is most reactive

optimum temperature

16

temp for IgM cold reactive antibody

1-6C/20-24C

17

IgG warm reacting antibody

37C

18

spontaneous clumping of rbc against a given serum

panagglutination

19

group O rgt RBC used for Ab ientification

panel cell

20

refers to a woman who had at least one pregnancy

primiparous

21

type of cold autoimmune hemolytic anemia in w/c a biphasic IgG Ab can be demostrated with anti-P specificity

Paroxysmal cold hemoglobinuria

22

D antigen thatis missing part of its typical antigenic structure

Partial D

23

refers to the chance that the alleged father is the biological father

Paternity index

24

diagrammatic chart for illustrating inheritance patterns of traits in a family study

Pedigree chart

25

detectable characteristics of genes

phenotype

26

initial treatment of elevated bilirubin using lights

phototherapy

27

extra blood sample collected during whole blood donation from a donor w/c is intended for serological test

pilot tube

28

fibrinogen containing liquid portion of anticoagulated blood

plasma

29

can be used as specimen for backward typing to detect antibodies however might present problem because it can bring about rouleaux formation

plasma

30

plasma prepared from whole blood subjected to heavy spin wc allow sedimentation of PLT leaving a plasma almost free of PLT

platelet poor plasma

31

plasma prepared from whole blood subjected to SOFT spin wc allow sedimentation of PLT leaving a plasma with high number of PLT

platelet rich plasma

32

products that are transfused in patients suffering from hypovolemia (dec plasma volume) or indicated among burn and shock patients

plasma volume expander

33

NSA meaning

normal serum albumin

34

PPF meaning

plasma protein fraction

35

NSA alb and globulin %

96% Alb + 4% Globulin

36

PPF alb and globulin %

83% Alb + 17% Globulin

37

Synthetic volume expanders

Crystalloids and Colloids

38

plasma derived volume expanders

NSA and PPF

39

Crystalloids [2]

Ringer's Lactate (Na, Cl, K, Ca, lactate ions)
Normal Saline Solution (0.85%-0.9% NaCl)

40

Colloids [2]

Dextran (6%-10%)
HES (Hydroethyl starch)

41

inability of patient to respond favorably after PLT transfusion thus desired increment in PLT not achieved

PLT Refractoriness

42

spontaneous agglutination of red cells by most normal adult sera regardless of blood group

polyagglutination

43

blood group system showing several allelic forms therefore rendering more than one alternative phenotype

polymorphism

44

refers to after child birth

postpartum

45

refers to after tranfusion

posttransfusion

46

relative strength of Ab present in given antiserum usually expressed in titer

potency

47

any substance that enhances Ag-Ab interaction from a given cell-serum mixture w/c may be used to detect low-titered Ab in routine testing

potentiator

48

0.2% in NaCl in glycine

LISS (Low Ionic Strength Saline Solution)

49

this medium has lower ionic strength that increases rate of antibody association
incubation may be shortened to 5-15 min if this medium is used

LISS (Low Ionic Strength Saline Solution)

50

positively charge polymer that reduces zeta potential by neutralizing the negative charge in red cell

polybrene

51

useful in identification of Ab in Kidd blood group system

polybrene

52

enhances Ab-Ag rxn by concentrating Ab in the mixture through water removal

Polyethylene glycol

53

PEG meaning

Polyethylene Glycol

54

refers to 2x2 grid used for gene combination

punnett square

55

system of procedures that ensures a lab to operate with most minimal errors

quality assurance

56

close monitoring of lab operations to allow maximum reliability of test result

quality control

57

in transfusion medicine, this refers to a person who benefits and receives blood transfusion

recipient

58

refers to the required speed in a given time to sediment particles from a fluid mixture

relative centrifugal force

59

RCF value

1.118 x 10^5 x radius x (rpm)^2

60

RCF meaning

Relative centrifugal force

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