BB LAB - Glossary IV Flashcards Preview

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Flashcards in BB LAB - Glossary IV Deck (45):
1

reciprocal of the highest dilution that shows a visible reaction

titer

2

inherited characteristic based from gene action

trait

3

administration of blood or its components intravenously

transfusion

4

type of transfusion
blood taken from a patient to be used for same patient

autologous transfusion

5

type of transfusion
transfer of blood directly from one person to another

direct transfusion

6

type of transfusion
used in infants with HDN, it refers to withdrawal of small volume of blood and subsequent replacement with compatible blood

exchange transfusion

7

type of transfusion
transfusion of blood stored in blood bag coming from a homologous donor

indirect transfusion

8

type of transfusion
blood tranfusion in utero

intrauterine transfusion

9

adverse rxn happening to a patient ff tranfusion of a unit of blood or its components

Transfusion reaction

10

batch test that includes ABO, Rh, and antibody screening test

Type and Screen (T/S)

11

set of guidelines developed to protect healthcare workers from exposure to infectious agents

universal precaution

12

vascular skin reaction commonly signalling allergic rxn

Urticaria (hives)

13

refers to type O and type AB individual s who are considered popularly as universal donor and universal recipient respectively

Universality concept

14

ability of red cell to survive in vivo after transfusion

viability

15

plasma cell dyscrasia characterized by excessive production of gamma M globulin

Waldenstrom's macroglobulinemia

16

colorless crystalline compound widely used as an anticlotting drug

Warfarin

17

anticoagulant drug that acts by inhibiting synthesis of vitamin K dependent factors: II, VII, IX, X

Warfarin

18

meaning of warfarin

Wisconsin Alumni Research Foundation + (Coum)arin

19

examples (?) of warfarin

coumadin
panwarfin
sofarin

20

refers to successive suspension of whole blood with NSS, centrifugation, and finally decanting completely the supernatant fluid. preferably done 3x to remove interfering substances w/c is present in plasma

washing

21

widely used in preparation of red cell suspension

washing

22

weaker variant of D-antigen that is detectable only through indirect antihuman globulin test

Weak D (D^u)

23

classification of Weak D (D^u)

Acquired D^u, Hereditary D^u, D^u variant/Mosaic

24

grade of Weak D (D^u)

high grade low grade

25

grade of Weak D (D^u)
does not require AHG for detection

high grade

26

AHG meaning

Antihemophilic globulin

27

grade of Weak D (D^u)
requires AHG for detection

low grade

28

thick gelatinous substance rich in hyaluronic acid that make up the matrix of the umbilical cord

Wharton's jelly

29

period of time when the disease is present but tested serologically negative

window period

30

soluble haptenic forms of A and B antigens capable of neutralizing their corresponding antibodies

Witebsky substance

31

blood group whose genes are located in the X-chromosome

Xg blood group

32

what antigen is seen in greatest frequency among females than males

Xg^a

33

net negative charge of red cell measured at the surface of shear; if it is reduced, red cells tend to become closer to each other and therefore easier to agglutinate

zeta potential

34

rxn that is influenced by amount of Ag and Ab from the cell-serum mixture; presence of either prozone or postzone often leads to false negative result

Zonal reaction

35

zone (zonal reaction)
zone of antibody excess (happens if more serum is added)

prozone

36

zone (zonal reaction)
zone of antigen excess (happens if red cell suspension is too heavy)

postzone

37

zone (zonal reaction)
zone of maximum or greatest rxn

Equivalence zone

38

For anti-a and anti-b what is the required potency

1:256

39

LISS Meaning

Low Ionic Strength Saline solution

40

Composition of LISS

0.2% NaCl in glycine

41

If LISS is used, incubation period may be shortened to -- mins

5-15 mins

42

The lower the ionic strength, the --- the rate of antibody association

Higher

43

Polybrene is useful in ID of Ab in what blood group system

Kidd

44

Former name of respiratory distress syndrome

Hyaline Membrane Disease

45

mixture of 0.1 M dithiothreitol (DTT) plus 0.1% cysteine-activated papain used to dissociate IgG molecules from erythrocytes showing a + DAT reaction

ZZAP

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