BB LEC - ABO Blood System Flashcards Preview

Botany > BB LEC - ABO Blood System > Flashcards

Flashcards in BB LEC - ABO Blood System Deck (67)
Loading flashcards...
1


most important system in transfusion and transplanta1on therapy

ABO BLOOD GROUP SYSTEM

2

the only blood group system in which individuals have an1bodies in their serum to an1gens that are absent from their RBCs

ABO BLOOD GROUP SYSTEM

3

drew blood from himself and five associates, separated the cells and serum, and then mixed each cell sample with each serum. He was inadvertently the first individual to perform forward and reverse grouping.

Landsteiner

4

• __ genes are dominant than O gene

A and B

5

__ genes are codominant

A and B

6

ABO genes are located on chromosome

9

7

ABO genes are inherited in a what manner following simple Mendelian genetics laws

codominant

8

H gene codes for what glycosyltransferases

L-fucosyltransferase

9

A gene codes for what glycosyltransferases

N-acetylgalactosaminyl- transferase

10

B gene codes for what glycosyltransferases

D-galactosyltransferase

11

Immunodominant sugar of H gene

L-fucose

12

Immunodominant sugar of A gene

N-acetyl-D- galactosamine

13

Immunodominant sugar of B gene

D-galactose

14

how many percent of all individuals possess the H gene.

99.99%

15

The forma1on of ABH antigens results from the interaction of genes at three separate loci what are these loci

(ABO, Hh, and Se)

16

A, B, and H an1gens are formed from the same basic precursor material called

(called a paragloboside or glycan)

17

On the __ day of fetal life, attachment of immunodominant sugars occurs on the RBC membrane and it is dependent on ABH genes inherited.

37th

18

antigens fully developed by what age

2-4 YEARS

19

is actually the precursor structure on which A and B an1gens are made

H antigen

20

The ___ genes are closely linked and located on chromosome 19

H and Se

21

The H and Se genes are closely linked and located on chromosome ?

19

22

what gene must be inherited to form the ABO antigens on the RBCs

H

23

what gene must be inherited to form the ABO antigens in secretions.

Se

24

what type of precursor substance
terminal galactose on the precursor substance is attached to the N-acetylglucosamine in a beta 1 → 4 linkage

type 2

25

what type of precursor substance
beta 1 → 3 linkage between galactose and N-acetylglucosamin

type 3

26

ABH antigens on the RBC are constructed on oligosaccharide chains of a type ?? precursor substance.

2

27


- are mostly naturally occurring antibodies that are
detectable 3 to 6 months after birth following exposure to ABO-likeantigensin theenvironment

ABO ANTIBODIES

28

ABO ANTIBODIES detectable when??

3 to 6 months after birth following exposure to ABO-likeantigensin theenvironment

29

are mostly IgM and react best at RT or below.

ABO ANTIBODIES

30

most anBbodies found in cord blood serum are of ?? origin

maternal

Decks in Botany Class (324):