BB Lec - Current Trends pt 2 Flashcards Preview

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Flashcards in BB Lec - Current Trends pt 2 Deck (17):
1

There are three commercial systems approved by the FDA for screening platelets for bacterial contamination:

BacT/ALERT (bioMérieux),
eBDS (Pall Corp.),
Scan- system (Hemosystem)

2

Measures bacteria by detecting a change in carbon- dioxide levels associated with bacterial growth

BacT/ALERT

3

This system (for screening platelets for bacterial contamination) provides continuous monitoring of the platelet sample–containing culture bottles, which are held for the shelf-life of the platelet unit or until a positive reaction is detected.

BacT/ALERT

4

culture-based systems

BacT/ALERT and eBDS

5

As the level of bacteria in the platelets at the time of collection can be low, samples are not taken until after at least how many hours of storage

24

6

measures the oxygen content of the air within the sample pouch following incubation for 18 to 30 hours.

eBDS system

7

in the eBDS system a decrease in oxygen level indicates the __

presence of bacteria

8

, is a laser-based, scanning cytometry method.

Scansystem

9

the first rapid test to detect bacteria in WBD platelets

Pan Genera Detection (PGD) test (Verax Biomedical)

10

an immunoassay that detects lipoteichoic acids on gram- positive bacteria and lipopolysaccharides on gram-negative bacteria. Both aerobes and anaerobes are detected.

Pan Genera Detection (PGD) test (Verax Biomedical)

11

are pooled ABO-matched, leukoreduced WBD platelets that have been cultured and are ready for transfusion.

Acrodose platelets

12

Acrodose platelets are produced in a closed system, they can be stored for how many days from collection

5

13

They provide a therapeutic dose equivalent to apheresis platelets and at a lower cost, but they do expose the recipient to multiple donors.

Acrodose platelets

14

Problem with 7 day storage of PLT

Septic transfusion rxns

15

PASSPORT meaning

Post approval surveillance study of platelet outcomes, release tested

16

Used to replace a large portion of plasma in PLT suspensions prepared from whole blood by buffy coat method

Platelet Additive solutions

17

Problem with 7 day storage of PLT

Septic transfusion rxns

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