Benign tumours of the bone but locally aggressive Flashcards Preview

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Flashcards in Benign tumours of the bone but locally aggressive Deck (14):
1

Radiolucent with increased density around the periphery

GCT

2

What is the cell of origin of GCT

osteoclast

3

who does GCT occur in

W>M 25-40s

4

where does GCT occur and symptoms

long bones
destruction of cortex and medullary and may expand into soft tissue

5

radiolucent with central density. lesion well circumscribes and may have surrounding sclerosis

osteoblastoma

6

what does osteoblastoma produce, prognosis and histology

osteoid and woven bone seen
self limiting
irregular bone and osteoid surrounded by osteoblasts
vascular stroma with pleomorphic spindle cells

7

what are the symptoms of osetblastoma and what does it present as

pain of long duration. swelling and tenderness
red tan in colour with haemorrhagic areas

8

increased uptake on bone scan

osteoblastoma

9

what tumour arises from notochord remnants

chordoma

10

where does chordoma occur

sacral region or base of skull. its a midline tumour

11

how does a chordoma grow and what are the symptoms

locally invasive and destructive
grows along a plane of least resistance such as a nerve root
can cause spinal symptoms

12

solitary midline lesions with bony destruction accompanying soft tissue mass - focal calcifications present half the time

chordoma

13

soft, blue-grey lobulated. gelatinous translucent areas and capsule present

chordoma

14

who do chordoma occur in

>40s F>M