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Flashcards in Biochemistry Deck (23):
1

What is the main storage form of lipids in the human body

triglycerides

2

Can fatty acids be used for gluconeogenesis

No

3

Why is lipid absorption necessary

for the absorption of the fat soluble vitamins

4

What is the first step of fat catabolism

lipolysis

5

where are fatty acids activated

the cytoplasm

6

where does beta oxidation occur

the mitochondrial matrix

7

what are fatty acids activated to

fatty acyl-CoA

8

When and where do ketone bodies form

liver mitochondria
Under the fasting state (hypoglycaemia)

9

What are ketone bodies used for

Diffuse into the blood and to peripheral tissues
Important molecules of energy metabolism for brain, heart muscle and renal cortex as they can be used in the TCA cycle


10

what can an increase in ketone bodies lead to

ketoacidosis

11

are ketone bodies toxic to peripheral tissue

no

12

Which hormones/compounds stimulate fatty acid synthesis

insulin
citrate

13

Which compounds inhibit fatty acid synthesis

glucagon

14

where are fatty acids synthesised

cytoplasm

15

what is the donor molecule for a growing fatty acid

malonyl-CoA

16

What is meant by 'citrate stimulates acetyl-CoA carboxylase allosterically’

It binds to a site separate from the catalytic cleft
It activates ACC when lots of citrate is present
Binding activates the catalytic activity

17

what are the 2 sources of nitrogen in the urea cycle

free ammonium
aspartic acid

18

what are Glucogenic amino acids used for

formation of glucose

19

what are Ketogenic amino acids used for

Can be completely oxidised by TCA cycle

20

Free ammonium is toxic, true/false

True

21

What type of products does catabolism produce

oxidised products
from reduced substrate

22

What type of products does anabolism produce

reduced biosynthetic products

23

where does the TCA cycle occur

occurs in the mitochondria