Flashcards in Biochemistry-Steroids Deck (24)
Where does cholesterol synthesis take place?
liver and intestines
Where in the cell does cholesterol synthesis take place?
What is the precursor for cholesterol synthesis?
What pathway is the greatest producer of Acetyl-CoA?
What is the regulatory enzyme of cholesterol synthesis?
What hormone promotes the action of HMG-CoA reductase?
What are 2 significant intermediates in cholesterol synthesis?
HMG-CoS, mevalonate, squalene, desmuterol
What is the function of cholesterol?
membran fluidity, precursor to all steroid hormones
What type of fatty acid increases cholesterol? What type of fatty acid decreases cholesterol?
Increases: saturated fats
Decreases: unsaturated fats
What other metabolite is formed from mevalonate?
What 2 substances act as conjugating agents to convert bile acids into bile salts?
What enzyme is involved in bile acid production?
What vitamin is needed for the activity of 7-alpha hydroxylase?
What are the 2 primary bile acids?
What the 2 secondary bile acids?
Where are bile acids formed?
Liver and intestines
Where are bile acids stored?
Where does bile acid reabsorption take place?
What are 2 functions of bile acids?
Testosterone is produced in which tissue?
Estrone and estradiol are produced in which tissue?
Ovaries and a small amount in the adrenal cortex
DHEA, progesterone, cortisol and aldosterone are produced in which tissue?
What is the precursor for steroid hormones?