Bipolar Flashcards Preview

Brain Things > Bipolar > Flashcards

Flashcards in Bipolar Deck (27)
Loading flashcards...
1
Q

What are first line treatments for bipolar?

A

Mood stabilizer

SGAs

2
Q

What is not considered a mood stabilizer?

A

Antidepressants

3
Q

SGAs have some antidepressant effect without inducing what?

A

Depression

4
Q

Lamotrigine is used in what two ways in bipolar?

A

Bipolar depression

Maintenance

5
Q

Lamotrigine has no effect on what part of bipolar?

A

Mania

6
Q

Lithium is used in what aspects of bipolar?

A

Mania
Depression
Maintenance

7
Q

What 2 anticonvulsants are approved in bipolar mania?

A

Valproate

Carbamazepine

8
Q

carbamazepine name brand for bipolar?

A

Equetro

9
Q

Which mood stabilizer is pregnancy C?

A

Lamotrigine

10
Q

Lamotrigine can cause what side effect if titrated too fast?

A

Rash

11
Q

What bad SE can lamotrigine cause?

A

Aplastic anemia

Agranulocytosis

12
Q

What is valproate therapeutic range?

A

50-125

13
Q

Supplement valproate therapy with what?

A

Vitamin d and calcium

14
Q

Valproate can cause what 4 scary serious side effects?

A

Hepatic failure
Teratogenicity
Pancreatitis
Mitochondrial disease

15
Q

Valproate can cause what two non serious side effects?

A

Weight gain

Tremor

16
Q

Supplement carbamazepine therapy with what?

A

Vit d and calcium

17
Q

Genetic testing with carbamazepine?

A

HLAB 1502 in Asians

18
Q

Carbamazepine can cause what 2 serious side effects?

A

SJS / TEN

agranulocytosis

19
Q

What is carbamazepine therapeutic range?

A

4-12

20
Q

What is lithium’s therapeutic range?

A

0.6-1.2

21
Q

Cannot use lithium in what patient population?

A

Renal impairment

Lithium is 100% really eliminated

22
Q

A decrease in salt intake will do what to lithium levels?

A

Increase lithium levels

23
Q

At what levels will lithium toxicity occur?

A

> 1.5

> 3.0

24
Q

Increase risk of serotonin syndrome with what mood stabilizer since its serotonergic?

A

Lithium

25
Q

Maintain adequate fluid intake with which mood stabilizer?

A

Lithium

8-12 glasses per day

26
Q

Do not change consumption of what with lithium therapy?

A

Salt

27
Q

4 mood stabilizers in bipolar?

A

Lithium
Valproate
Lamotrigine
Carbamazepine