BIS 103: Glutathione, Pentose phosphate pathway Flashcards
1
Q
structure of glutathione
A
gamma E - cys - glyceine
2
Q
glutathione synthesis
A
gamma E CO2- becomes acyl phosphate
Cys amino attacks acyl phosphate
Cys CO2- becomes acyl phosphate
gly amino attacks acyl phosphate
3
Q
enzyme that reduces glutathione
substrate?
A
glutathione reductase
2 NADPH
4
Q
oxidative Pentose phosphate pathway-result
A
makes ribose-5-P
ox, so reduces to make NADPH
5
Q
NADPH functions
A
- used to reduce ECG
- makes molecules (biosyn)
- in B-ox
6
Q
where does Pentose phosphate pathway occur?
A
cytosol - easily reversible
7
Q
nonoxidative Pentose phosphate pathway - result
A
makes G6P
8
Q
carbon shuttlers - ox or nonox?
A
nonox
transketolase - moves 2, uses TPP
transaldolase - moves 3, uses schiff base
(lys -NH-c=c OH
9
Q
1st enzyme in ox Pentose phosphate pathway
A
G6p dehydrogenase
10
Q
REVIEW PDH
A
lsfjka fuck fine >:[
