[bleedingIx] Flashcards
1
Q
A
extrinsic
2
Q
A
INR
3
Q
A
0.9-1.2
4
Q
A
I II V VII X
5
Q
A
Warfarin
6
Q
A
warfarin
7
Q
A
INR/prothrombin
8
Q
A
factor VII
9
Q
A
increased consumption of multiple clotting factors
10
Q
A
35-45 seconds
11
Q
A
the intrinsic
12
Q
A
heparin
13
Q
A
binds to anti-thrombin III inhibitor
AT3 activates and inhibits thrombin
thrombin is responsible for fibrin deposition
14
Q
A
warfarin inhibits synthesis of 1972 factors - K dependent.
7 is only in extrinsic pathway
15
Q
A
converts fibrinogen to fibrin
16
Q
A
10-15 seconds
17
Q
A
fibrin degradation products
released from the x-linking during fibrinolysis
18
Q
A
DIC
PE
DVT
19
Q
A
two small cuts in forearm
20
Q
A
<10 mins
21
Q
A
PFA-100
22
Q
A
platelet function analyzer 100
23
Q
A
collagen + adrenaline
collagen + ADP
24
Q
collagen + ADP are abnormal what does this indicate
A
platelet dysfunction is likely - further testing
25
[bleedingIx]: PFA -100: if collagen + adrenaline is normal but collagen + ADP are abnormal what does this indicate
aspirin ingestion
26
[bleedingIx]: which test do the haemophilias affect
APTT
27
[bleedingIx]: what method of drug delivery is absolutely CI in bleeding disorders?
IM
