Block 1 W3 Flashcards

1
Q

Proteoglycan

A

Glycoprotein found in the extracellular matrix which fills the spaces between cells

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2
Q

Tonicity

A

Ability of a solution surrounding a cell to cause it to gain or lose water. It is a measure of solutes

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3
Q

Sinusoid capillaries

A

Found in the liver, bone marrow and spleen

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4
Q

Marker of inflammation

A

C-reactive protein

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5
Q

Cause of oedema

A

Inflammation, venous or lymph obstruction and lack of proteins

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6
Q

Morula

A

Mass of indistinguishibale blastomeres which are still totipotent at this stage

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7
Q

Which stage of the embryo does protein synthesis and ATP production begin?

A

Blastocyt

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8
Q

What is the proportion of intracellular fluid in the body?

A

2/3

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9
Q

Sessile, amoebae, ciliates and flagellates

A

Types of protozoa

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10
Q

Virus in a capsid

A

Enveloped virus which has a capsid from the host cell

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11
Q

Virus without capsid

A

Complex virus

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12
Q

Which vessels generate blood pressure?

A

Large elastic arteries that expand and recoil

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13
Q

Which vessels maintain vascular pressure?

A

Arterioles which change shape when transmitting blood to the capillaries

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14
Q

Dense-> least dense blood component

A

Erythrocyte -> buffy coat (containing WBC and platelets) -> plasma

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15
Q

Causes of low plasma protein

A

Low protein diet, kidney/liver disease

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16
Q

Constantly open channel proteins

A

Aquaporins, which allow the free transport of water

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17
Q

Apical surface

A

Area on epithelia where it is in contact with the lumen

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18
Q

Heterophilic

A

Adhesion that requires different molecules to bind

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19
Q

Gram positive bacteria

A

Have a lipoglycan cell wall and a layer of peptidoglycan

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20
Q

Proteogylcan

A

Mesh made of gylcoproteins, where collagen and elastin are held and bind to cells via receptors

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21
Q

Basal lamina

A

Thin membrane between epithelial cells and connective tissue consisting of collagen and glycoprotein lamina which is on the apical surface and binds to integrins

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22
Q

Stratified cuboidal epithelia

A

For secretion of sweat glands and salivary glands and protection

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23
Q

Basolateral surface

A

Epithelial surface joined to the basement membrane

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24
Q

Catenins

A

Link cadherin intracellularly to the actin cytoskeleton

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25
Brush border
Apical epithelial surface with microvilli
26
Humoral immunity vs cell-mediated immunity
Humoral immunity is adaptive immunity via antibody production. Cell-mediated immunity is the destruction of infected cells by T lymphocytes
27
Integrins
Transmembrane protein bound to the basement membrane as a link between ECM and actin cytoskeleton. It has heterodimer interactions for signal transduction pathway. It consists of an alpha and beta chain and is found in connective tissue.
28
Fenestrated capillary
Found in kidneys and small intestine
29
Gram positive bacteria
Lipoglycan cell wall
30
Areolar connective tissue
Wraps around muscles and surrounds the organs and blood vessels
31
Desmosomes
Anchoring junctions which prevent cells from being pulled apart.
32
Tight junction
Creates cell polarity by preventing passage of molecules beneath apical surface
33
Which vessel conducts blood away from the heart and towards the tissues?
Medium muscular arteries
34
Tonicity
No of solute particles
35
Osmolarity/osmolality
Conc of solute particles
36
Medium veins
Carry blood towards the heart and have small amounts of smooth muscle. Tunica externa is thinner than tunica media. Less smooth muscle than large veins
37
Large veins
Carry blood towards the heart. Contains cross sectional bundles of smooth muscle More smooth muscle than large veins
38
What is a measurement for inflammation occurrence?
Native C-reactive protein
39
What attaches epithelial cells to the basement membrane?
Hemidesmosomes
40
Adhesive glycoprotein in connective tissue
Fibronectin
41
What provides strong mechanical attachments between adjacent cells?
Adheren/ anchoring junctions
42
Extracellular fluid
Transcellular, interstital and plasma
43
Least common WBC
Basophils
44
Saprophyte
Organism which feeds on dead matter
45
Fungi reproduction
Budding or asexually
46
Humoural immunity
Adaptive immunity via antibodies produced by B cells
47
Cumulus cells
Layer of cells around the ovum after fertilisation which protects it
48
Primitive streak
Streak down the embryo in the epiblast with the movement of cells to form the mesoderm layer
49
Simple squamous epithelia
Flat layer of cells for diffusion
50
Stratified squamous epithelia
Flattened layer of cells for protection in the oesophagus, mouth and vagina
51
Stratified cuboidal epithelia
Flattened layer of cells for secretion and protection
52
Transitional epithelia
Lines the bladder and urethra and can expand to hold urine
53
Ground substance
Layer of connective tissue where diffusion of oxygen, nutrients and waste occurs
54
Laminin
Adhesive glycoprotein in the basal lamina which provides a bridge between cells and connective tissue for anchoring
55
Integrin
Adhesive glycoprotein formed of alpha and beta chain. Binds to fibronectin and laminin for connection to cytoskeleton.
56
Controls filling of capillaries and contributes to vascular pressure
Arterioles
57
Transcellular fluid
In epithelia lined spaces such as synovial fluid, cerebrospinal fluid.
57
Cadherin
Transmembrane protein which binds to other cadherin via homodimer interaction and intracellular segment binds to catenin
58
Tight junctions
Creates cell polarity by sealing adjacent epithelial cells, formed of claudin proteins
59
Direct cell attack and antibodies
Lymphocytes
60
Large veins
Transport blood back to the heart and contain smooth muscle in the tunica media. Thickest layer is the tunica externa.
61
Sessile
Non-moving protozoa
62
Adhesive glycoprotien in connective tissue which binds to fibrin, collagen and integrin
Fibronectin
63
Hemidesmosomes
Attaches epithelial cells to basement membrane