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Flashcards in Block 3 Deck (23):
1

How is cellular damage caused during the acute phase of Hepatitis B?

During the acute phase of infection Hep B surface antigens are presented on the surface of hepatocytes by MHC 1 cells and attacked by CD8 killers

2

When what condition causes elevated ACHe in maternal blood?

Spina bifida

3

What three enzymes require thiamine to function?

Transketolase, pyruvate dehydrogenase, and alpha-ketoglutarate.

4

Mosaicism is a rare, but important cause of down syndrome.

Don't forget!

5

What is one genetic condition that is associated with a bicuspid aortic valve?

Turner syndrome (XO)

6

What is one cytokine responsible for osteoclast differentiation?

M-CSF

7

Which cells have a MHC-1 molecule on their surface with a beta-2 microglobulin?

All cells present intracellular pathogens this way to CD8 cells

8

Antibodies against what are important for preventing the infectivity of pneumococcus?

Antibodies against the capsule are responsible for preventing pneumococcal infectivity.

9

How long does it take for a vasectomy to become fully effective?

About three months; before this time there are still viable sperm that can be passed in ejaculate.

10

What does damage to the radial nerve at the head of the radius cause?

Weakness, but not sensory deficits

11

What do reticulocytes have that mature RBCs do not?

Residual rRNA

12

How will a larger ejection fraction be measured?

There will be a larger gap in the x-axis of the cardiac curve.

13

How does hCG cause ovulation?

hCG causes a surge in LH that results in ovulation.

14

What does disruption of the Kozak consensus cause?

Inhibited binding preventing translation.

15

If heme synthesis is inhibited what will happen to the size of the RBCs?

They will shrink.

16

Why is tazobactam given with some members of the penicillin class of drugs?

Tazobactam inhibits penicillinase

17

What is used to treat giardia?

metronidazole

18

Where is PPAR-gamma located in the cell?

PPAR-gamma is located in the nucleus

19

What is the pharmacological role of N-acetylcysteine (apart from treating tylenol poisoning)?

It helps to reduce disulfide bonds and liquefy mucus

20

What effect do B-Blockers have on renin levels?

B-Blockers decrease the level of circulating renin.

21

What is the formula for specificity?

TN/(TN+FN)

22

PBC acts like GVHD

Know this!

23

What cell type predominates in the ovary?

Simple cuboidal epithelium