Block 5 Review Flashcards Preview

Neuro Final Review > Block 5 Review > Flashcards

Flashcards in Block 5 Review Deck (12):
1

What looks dark on T1 and T2 MRI?
What looks light?

Dark - CSF, edema, bone, air, calcium, some lesions
Middle - white and gray matter
Light - fat, blood, gal - contrast material

2

What stage has low amplitude, high frequency beta wave?

Awake - in presence of Orexin
REM Sleep!

3

What is seen in an EEG of a seizure?

Low frequency, high amplitude waves outputed from the cortex. Thalamocortical oscillations synchronize firing across the thalamus.

4

Where does AD cause neurofibrillary tangles?

Hippocampus

5

Difference between Naloxone and Naltrexone?

Naloxone - for opioid OD
Naltrexone - for opioid addiction

6

What is the significance of the GABAergic neurons in the VPLO?

"Sleep switch" that inhibits ARAS nuclei & orexin neurons

7

What does Melanin-concentrating hormone do?

Promotes REM sleep

8

What is the significance of ARAS?

Cholinergic, dopaminergic and histaminergic neurons that promote wakefulness!

9

What does dexamethasone inhibit?

Prostaglandin synthesis

10

What does a high MAC value indicate? What has the highest MAC value?

High MAC = low potency
Low MAC = high potency
Nitrous Oxide has highest MAC

11

What has the lowest MAC value of the anesthetics?

Halothane - it is very potent!

12

What is the MOA for Ketamine?

Potent, high affinity, NMDA receptor antagonist