Flashcards in Blood Deck (20):
why is blood a type of CT?
has all the elements: cells( formed elements) + "ECM/ground substance" (plasma)
% of RBCs in blood. (male is 50%, female is 40%)
pale yellow liquid that holds RBCs in suspension. Or blood minus the cells
define: blood serum
plasma without the clotting factors. Or blood without cells and clotting factors.
define: buffy coat
chunk of leukocytes + platelets in centrifuged blood
what is in blood plasma? (3 plasma proteins, 4 organic compounds + inorganic salts)
albumin, globulins alpha, beta and gamma, + fibrinogen
organic compounds: amino acids, vitamins, hormones, lipoproteins
What are the 3 general types of blood cells/formed elements in blood?
1) erythrocytes, 2) Thrombocytes, 3) leukocytes
O2 storage + transport, males have more than females, lifespan = 120 days.
anucleated, biconcave discs (except for immature RETICULOCYTES
what are immature erythrocytes called
what do erythrocytes look like
annucleated, biconcave discs
what happens to erethrocytes if improper lab technique?
hemolysis - leakage of Hgb from RBCs, RBC will deflate into a pale "ghost"
what happens to erythrocytes in stasis?
will form ROULEAUX stacks (presence indicates clotting problems)
pathoogy of erythrocytes
anemia (down hematocrit), polycythemia (up hematocrit), erythrocytosis (sickle cell - causes capillary clogging)
lifespan of thrombocytes:
what are thrombocytes
platelets. v small. fragments of MEGAKARYOCYTES (bone marrow)
why do platelets have an open canalicular system?
allows for storage
why are there microtubules in platelets?
are thrombocytes nucleated?
what is inside a platelet?
1) dense bodies (sigma granules, Ca, pyrophosphate, ATP + ADP), 2) alpha granules (fibronogen + PDGF), 3) EGF 4) proteins