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Flashcards in Blood Deck (20):
1

why is blood a type of CT?

has all the elements: cells( formed elements) + "ECM/ground substance" (plasma)

2

define: hematocrit

% of RBCs in blood. (male is 50%, female is 40%)

3

define: plasma

pale yellow liquid that holds RBCs in suspension. Or blood minus the cells

4

define: blood serum

plasma without the clotting factors. Or blood without cells and clotting factors.

5

define: buffy coat

chunk of leukocytes + platelets in centrifuged blood

6

what is in blood plasma? (3 plasma proteins, 4 organic compounds + inorganic salts)

plasma proteins:
albumin, globulins alpha, beta and gamma, + fibrinogen

organic compounds: amino acids, vitamins, hormones, lipoproteins

7

What are the 3 general types of blood cells/formed elements in blood?

1) erythrocytes, 2) Thrombocytes, 3) leukocytes

8

describe erythrocytes

O2 storage + transport, males have more than females, lifespan = 120 days.

anucleated, biconcave discs (except for immature RETICULOCYTES

contain Hgb.

9

what are immature erythrocytes called

reticulocytes

10

what do erythrocytes look like

annucleated, biconcave discs

11

what happens to erethrocytes if improper lab technique?

hemolysis - leakage of Hgb from RBCs, RBC will deflate into a pale "ghost"

12

what happens to erythrocytes in stasis?

will form ROULEAUX stacks (presence indicates clotting problems)

13

pathoogy of erythrocytes

anemia (down hematocrit), polycythemia (up hematocrit), erythrocytosis (sickle cell - causes capillary clogging)

14

lifespan of thrombocytes:

8-12 days

15

what are thrombocytes

platelets. v small. fragments of MEGAKARYOCYTES (bone marrow)

16

why do platelets have an open canalicular system?

allows for storage

17

why are there microtubules in platelets?

structural support

18

are thrombocytes nucleated?

no

19

what is inside a platelet?

1) dense bodies (sigma granules, Ca, pyrophosphate, ATP + ADP), 2) alpha granules (fibronogen + PDGF), 3) EGF 4) proteins

20

what is the difference bw granular and agranular leukocytes?

Granular white blood cells contains numerous granules in the cytoplasm, & their nuclei are lobed. Agranular white blood cells have few or no granules in the cytoplasm & have a large spherical nucleus. Granular white blood cells are produced in the bone marrow, while agranular white blood cells are produced in lymph tissue,

granular leukocytes (neutrophils, eosinophils, basophils)

agranular leukocytes (lymphocytes, monocytes)