Blood Flashcards

1
Q

Plasma

A

liquid that acts as ECM component in blood, where RBCs, WBCs, and platelets are suspended

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2
Q

Main Plasma Proteins

A
  • Albumin
  • Gamma Globulins
  • Fibrinogen
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3
Q

Albumin

A

maintains osmotic pressure in blood

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4
Q

Gamma Globulin

A

immunoglobulins or antibodies

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5
Q

Fibrinogen

A

clotting agent, fibre portion that is converted by thrombin into fribrin

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6
Q

Platlets

A

fractions of cells, no nucleus

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7
Q

Normal Hematocrit Volumes
Pasma:
WBCs
RBCs

A

Plasma: 55% (Top)
WBCs: 1% (Middle)
RBCs: 45% (Bottom)

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8
Q

Type A Blood

A

cell has A antigen and B antibodies

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9
Q

Type B Blood

A

cell had B antigen and A antibodies

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10
Q

Type AB Blood

A

cell has both A and B antigens but no antibodies

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11
Q

Type O Blood

A

cell has no antigens but both A and B antibodies

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12
Q

2 Categories of Leukocytes

A

Granular

Agranular

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13
Q

Agranular

A
  • do not have specific granules

- include Lymphocytes and Monocytes

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14
Q

Granular

A
  • visible granules

- include Basophils, Neutrophils, and Eosinophils

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15
Q

Agranular Leukocytes

A

Lymphocytes

Monocytes

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16
Q

Granular Leukocytes

A

Basophils
Neutrophils
Eosinophils

17
Q

Lymphocytes

A

25-30% of all leukocytes

18
Q

3 Functional Categories of Lymphocytes

A
B Lymphocytes (B Cells)
T Lymphocytes (T Cells)
Null Cells
19
Q

B Lymphocytes

A
  • humorally mediated immune response

- develop in bone marrow and produce antibodies, differentiate into plasma cells

20
Q

T Lymphocytes

A
  • cell-mediated immune response (does not involve antibodies)
  • develop in thymus
  • release singling molecules (cytokines)
21
Q

Monocyte

A
  • 3-8% of all WBCs
  • kidney shaped nucleus
  • differentiate into macrophages
22
Q

Neutrophils

A
  • 60-70% of WBCs
  • first responders to infection and microbes
  • multi-lobed nucleus is connected by chromatin threads
23
Q

Eosinophils

A
  • less than 4% of WBCs
  • first responders to parasites and phagocytose antigen-antibody complexes
  • bi-lobed nucleus connected by chromatin
24
Q

Platelets (Thrombocytes)

A
  • less than 14 day lifespan
  • no nucleus
  • become activated when endothelial lining of blood vessel is disrupted and they come into contact with sub endothelial collagen