blood composition and function Flashcards
what does blood act as
transport medium
what is plasma
liquid with the clotting factors
what is serum
plasma without the clotting factor
name a clotting factor
fibrinogen
what is clotting time
8-15 mins
what prevent clotting
anticoagulants
example anticoagulants
EDTA
Heparin
what does centrifugation priduced
wplasma layer
Buffy layer
Red layer
what is PCV (packed cell volume) calculated by
height of red (PC)/height of sample
how can blood be stored
whole blood
packed red blood cells (neoplasm)
platelet rich plasma
how are blood donations treated
heat treated
what is a risk of blood transfusion
acute haemolytic transaction reaction
what is the worst case of acute haemolytic transaction reaction
A antibodies given to O recipient
what do all blood cells evolve from
haemocytoblast
where does blood cell differentiation occur
bone marrow
what is making of ‘new blood called’
haematopoiesis
what is making of erythrocytes called
erythropoiesis
what is erythropoiesis stimulated by
lack of O2 detected by kidneys
EPO secreted
EPO acts on erythrocyte precursors and increases production in red blood marrow
types of leukocytes
neutrophils esinophils basophils lymphocytes monocytes
what regulate the level of blood cells in circulation
colony stimulating factors
what is erythrocyte sedimentation
how quick erythrocytes settle at the bottom
how does erythrocyte sedimentation differ
quicker in men
increases with age and inflammatory diseases
what are platelets
cell fragments that are involved in the clotting processss
how is cholesterol calculated
HDL + LDL + 20% triglyceride value
