Blood Glucose Concentration Flashcards Preview

HUBS191 Endocrine System > Blood Glucose Concentration > Flashcards

Flashcards in Blood Glucose Concentration Deck (11)
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1

BGC reference range (fasting)

3.5-6 mmol/L

2

metabolic effects of insulin

muscle: glucose and amino acid uptake increase, glycogen and protein synthesis fat: fat synthesis Liver: net glucose uptake increases, glycogen synthesis

3

diabetes mellitus symptoms

hyperglycaemia, glycosuria, polyuria, polydipsia, polyphagia

4

glucagon metabolic effects

liver: glycolysis, gluconeogenesis, ketone synthesis

5

hormones that increase blood glucose

glucagon, cortisol, adrenaline

6

insulin negative feedback loop

7

type I diabetes mellitus

  • normally diagnosed during childhood
  • due to insulin producing beta cells being destroyed (autoimmune disease) so insulin levels low
  • treatment = insulin injections with regular BGC testing
  • 10% of cases

8

diabetes mellitus type II

  • usually in adults
  • caused by cells resistant to insulin's signal to store fuel e.g. fewer receptors
  • insulin level also lowed
  • treament = insulin injections, drugs promoting insulin release e.g. incretins, exercise
  • risk factors = obesity, ethnicities, genetics

9

complications of diabetes

  • hyperglycaemia
  • atherosclerosis
  • kidney disease
  • nerve damage
  • blindness

10

glucagon negative feedback loop

11