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Flashcards in Blood Groups Deck (16):
1

When are IgG antibodies mainly expressed?

Foeto-maternal transmission or in response to blood transfusions

2

When are IgM antibodies mainly expressed?

In response to components in food that mimic A & B antigens

3

What shape is an antibody and where can the Fab and Fc sites be found?

Y shaped. Fab on the top branches of the Y and Fc on the stalk of the Y

4

What molecule do the FUT 1 and FUT 2 genes code for?

Histamine

5

What molecules do the A and B genes code for?

Glucosyl transferases

6

Name the extra sugar molecules that A antigen and B antigen possess respectively.

A: N-Acetylgalactoseamine
B: Galactose

7

Which naturally occurring antibodies do people with O antigens possess

Anti-A
Anti-B

8

Which naturally occurring antibodies do people with A antigens possess

Anti-B

9

Which naturally occurring antibodies do people with B antigens possess

Anti-A

10

Which naturally occurring antibodies do people with A & B antigens possess

None

11

Which antigen is implied as negative in the commonly used phrase, 'Rhesus Negative'?

D antigen

12

How can Rhesus D immunisation (particularly problematic during pregnancy), be prevented?

Anti-D prophylaxis - given to D negative mothers at 28 weeks and 40 weeks (delivery)

13

People with which blood group are know as 'universal receivers'?

AB

14

People with which blood group are know as 'universal donors'?

O

15

When does a rhesus conflict occur?

Rhesus -ve mother and rhesus +ve father & foetus

16

Which antibody is most dangerous?

IgM - it can agglutinates the blood