Body Fluid Compartments Flashcards Preview

Renal Midterm > Body Fluid Compartments > Flashcards

Flashcards in Body Fluid Compartments Deck (57)
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1

what is the normal osmolality that we should look for

290 mOsm

2

how do you calculate total body water TBW

0.6*BW(body weight)

3

what is the third space

transcellular compartment or locations that the body should not have water

4

how do you calculate ICF or intracellular fluid

0.4*body weight OR 2/3 of TBW(total body water)

5

how do you calculate ECF or extracellular fluid

0.2*BW or 1/3 of TBW

6

how do you calculate interstitial fluid

0.75*ECF

7

how do you calculate plasma volume

0.25*ECF

8

How do you calculate venous volume

0.8*plasma volume

9

how do you calculate ECV or effective circulating volume

0.2*plasma volume

10

what age group has the highest percentage of TBW

infants and this goes down with age

11

where do we gain water input

drinking, food, and carb metab

12

where do we lose water

feces, sweating, insensible perspiration, and urine

13

what are our main extracellular ions

Na and Cl

14

what are our main intracellular ions

K

15

where are protein levels highest

in ICF and vascular compartments

16

what are the main proteins we are concerned with

albumin and globulins

17

what can be used to help measure plasma volume?

albumin that is radiolabeled

18

what can't we measure directly

ICF and ISF

19

how do we measure TBW experimentally

heavy water or antipyrine

20

how do we measure ECF experimentally

heavy Na, l-iothalamate, thiosulfate, inulin

21

what is the gibbs donnan effect

the negative charge of proteins within the vasculature causes the Na+ and K+ concentrations to be slightly higher than expected

22

what is ECF osmolality driven by

Na

23

where is the most Na found

vasc>interstitium>ICF due to action of NaK ATPase

24

what does a disrupted NaK pump cause an increase in

ICF [Na] this causes cellular swelling

25

what is ICF osmolality driven by

K

26

what are the two ways to estimate plasma osmolality

2*[Na]

2*[Na] + glucose/18 + urea/2.8

27

the ECF and ICF are highly permeable to what

water but NOT electrolytes

28

the capillary membrane is highly permeable to what

small ions which drive the starling forces

29

what main force favors filtration? opposes filtration

Pc; Pi_c

30

what are some common causes that increase Pc

-increased arterial pressure
-increased venous pressure
-decreased precapillary resistance
-increased postcapillary resistance