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Flashcards in Bone & Joint Infections Deck (17):
1

List the organisms in order of frequency of cases caused that are responsible for osteomyelitis.

S. aureas (80%)
S. pyogenes
M. tuberculosis
(Salmonella*)

2

List some of the symptoms and signs that are present in cases of osteomyelitis.

Fever
Painful, swollen site
Paraplegia
Reduced movement

3

What is C-reactive protein?

A protein present in blood plasma which increases in number upon inflammation

4

Name the 4 investigations that are carried out when diagnosing osteomyelitis.

X-ray
CT/MRI/Bone Scan
Blood sample
Pus

5

How is osteomyelitis treated?

Standard empirical:
FLUCLOXACILLIN, fucidin

Alternative empirical:
Fucidin, erythromycin
*Ciprofloxacin (salmonella)
Isoniazid, Rifampicin, Pyrazinamide, Ethambutol (tuberculosis)

6

Where is septic arthritis most likely to occur (three sites)?

Knee
Hip
Lumbo-sacral Spine

7

List three predisposing conditions to septic arthritis.

Rhumatoid arthritis
Infection of joint
Prosthetic joint

8

Name some causative organisms of septic arthritis.

S. aureus
S. pyogenes
M. tuberculosis
S. epidermis
Salmonella
Brucella

9

Which three methods are used to diagnose septic arthritis?

Blood culture
Joint aspirate (i.e. drain fluid from joint)
Joint X-ray

10

How is septic arthritis treated?

Standard Empirical:
FLUCLOXACILLIN, fucidin

Alternative Empirical:
Erythromycin

11

What is Reiter's Syndrome?

Arthritis, conjunctivitis & urethritis
Possibly caused by chlamydia

12

Where do organisms settle in the bone in haematogenous spread?

Metaphysis

13

For salmonella based osteomyelitis, what is the most common predisposition?

Sickle cell disease

14

For brucella based osteomyelitis, what is the most common predisposition?

Travel/Foreign born

15

What type of organism based osteomyelitis is likely to arise in children under the age of 5 years?

H. influenzae based

16

Which type of organism based osteomyelitis is most likely to arise in people with cases of prosthesis (i.e. prosthetic limbs)?

S. epidermis

17

E. coli based osteomyelitis is most likely to arise from what predisposition?

UTI (urinary tract infection)