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Flashcards in Bordetella Deck (31):
1

Bordetella causes kennel cough and ____ in swine 

atrophic rhinitis 

2

Bordetella are aerobic bacteria that infect the ______ of hosts 

ciliated respiratory epithelium 

3

Which Bordetella species have flagella?

Bordetella bronchiseptica and B. avium 

4

True/False: Bordetella is highly variable

True

difficult for vaccination 

5

Which species of Bordetella causes porcine atrophic rhinitis and Canine kennel cough?

Bordetella Bronchiseptica 

*can lead to bronchopneumonia in many species

6

What species of Bordetella causes Turkey Coryza?

Bordetella Avium 

7

What virulence factor does Bordetella express, but only in warm environments of around 37 degrees? 

BvgAS- bordetella virulence gene

*avirulent at 25 degrees 

8

What kind of disease is associated with Bordetella?

respiratory

9

Bordetella can cause _____ 

hemagglutination 

10

What important virulence factor of Bordetella helps with adherence to the respiratory tract?

Tracheal colonization factor

*This is only expressed by Bordetella Pertussis. Targets trachea. Not expressed in Bordetella Parapertussis or Bronchiseptica

11

What outer membrane proteins does Bordetella have?

Pertactin and Brk (Bordetella resistance to killing)

12

What siderphore is particular to Bordetella species?

Alcaligin 

13

What type of secretion system does Bordetella use?

Type III secretion system 

14

What are the 5 exotoxins important with Bordetella and what do they do?

Tracheal cytotoxin- toxic to cells within the trachea 

Dermonecrotic toxin- destruction of turbinates in atrophic rhinitis

Adenylyl cyclase toxin- results in fluid loss

Pertussis Toxin- only active in B. pertussis and results in fluid loss

Osteotoxin- lethal to tracheal and bone cells 

15

How is Bordetella transmitted?

Direct Contact 

*needs close contact 

16

Bordetella leads to depression of respiratory _____ and can lead to secondary ____ complications 

depression of respiratory clearance

secondary pneumonia complications 

17

In pigs, nasal irritation associated with Bordetella can open the doors for _____ to infect

Pastuerella Multocida 

18

What is the medical term for kennel cough?

Canine infectious tracheobronchitis 

19

What other pathogens can co-infect with Kennel cough?

parainfluenza virus

adenovirus

canine herpesvirus 

20

Dogs with ____ are at a higher risk for develping pneumonia associated with Bordetella because they are immunosuppressed 

distemper 

21

True/False: Coughing is common in cats with Kennel cough?

False

*couging is not common with cats 

22

Atrophic rhinitis is associated with what two bacteria?

Bordetella Bronchiseptica and Pasteurella Multocida 

 

Note on image: KNOW THESE IMAGES. B and C show pig after infection when there has been erosion of nasal turbinates 

A image thumb
23

Atrophic rhinitis usually occurs in ____ pigs and _____ are carries that can spread the bacteria to their progeny and other progeny 

occurs in young pigs

Sows are carriers 

24

True/False: Turkey Corya is highly infectious and causes high mortality 

False

it is highly contagious in young turkeys but has a low mortility rate of less than 5%

25

What does Turkey Coryza cause in the trachea?

tracheal degenration and flattening making it hard for the bird to breath

A image thumb
26

If Bordetella comes into the mix with Snuffles (P. multocida) then it can cause _____ in rabbits

Bronchopneumonia 

27

Bordetella depresses the immune system by telling ____ cells not to secrete as much 

dendritic cells 

28

Bordetella are strict ____

aerobes

*they are in the respiratory tract 

29

What is the best way to control Atrophic Rhinitis?

vaccines are available for pigs

CLEAN facility

*not treatable in advanced cases

30

What is the best way to control Canine tracheobronchitis?

ventilation of kennels to keep the air moving

*vaccination doesn't help much 

31

Is there a vaccine available for Turkey Coryza?

Yes