Cancer

Question 1

Oncogenes

Answer 1

Ras
Myc - upregulated due to increased chromatin accessibility - upregulates CycD
BCR-ABL Gene fusion between 9 and 22, spontaneously active Tyr Kinase causes uncontrollable celldiv

Question 2

Tumour Suppressor

Answer 2

p53, p16, RB

Usually needs loss-of-heterozygosity (except p53)