Carbohydrates Flashcards
(25 cards)
oxidation of glucose yields
glucuronic acid
reduction of glucose yields
sorbitol
gluc + fruc
sucrose
non reducing sugar
sucrose
only glut transporter requiring insulin
glut 4
glut 2 is found in the __ of SI; glut 5 __
basement membrane
lumen
MC type of glycolysis
Embden-Meyerhof Parnas pathway
RLS of glycolysis
F6P to F1,6 BP
Enzyme: PFK-1
1 step in glycolysis producing NADH
G3P to 1,3 BPG
Enzyme: G3P DH
glycerophosphate shuttle vs malate aspartate shuttle ATP yield
glycerophosphate shuttle 1.5 ATPs
malate aspartate shuttle 2.5 ATPs
1,3 BPG to 2,3 BPG in RBCs aka
Rappaport Luebering shunt pathway
coenzyme of PDH
TLC FN
thiamine, lipoic acid, coA, FAD, NAD
how As inhibits PDH
binds to lipoic acid
MCC of congenital LA
PDH def
RLS of TCA cycle
isocitrate to AKG
Enzyme: isocitrate DH
fluroacetate inhibits
isocitrate
citrate to isocitrate
ATP yield for TCA
10 ATPs
total ATP yield in oxidation of glucose
30 or 32 ATPs
RLS of gluconeogenesis
F 1,6 BP to F6P
F 1, 6 BPase
3 rxns carboxylases
Pyruvate → Oxaloacetate (Pyruvate carboxylase)
Acetyl CoA → Malonyl CoA (Acetyl CoA carboxylase)
Propionyl CoA → Methylmalonyl CoA (Propionyl CoA carboxylase)
C4 epimer of glucose
galactose
converts gluc to sorbitol
aldose reductase
humans cannot produce vit C bec of absence of
L-gulonolactone oxidase
RLS of PPP
G6P to 6 phosphogluconate
Enzyme: G6PD
