Cardiac Lecture 4 Flashcards
Velocity is INVERSELY related to ________ ______ ________
Cross-sectional area
Volume per unti time is _______
Flow
Distance per unit time is ________
Velocity
Velocity Formula
V=Q/A Where V=Velocity Q=Flow A=Cross-sectional area
Velocity of the bloodstream depends on _____ and ____________
blood flow and vacular cross-sectional area
Blood flow is driven by the differences in total energy between ___ ____
two points
Three primary factors that determine to resistance in a single blood vessel
vessel diameter (or radius), vessel length and viscosity of the blood
The most important factor in changin resistance to flow in a vessle is ________
vessel diameter because of contraction and relaxation of vascular smooth muscle in the vessel wall
Blood viscosity usually stays the same except when ________ changes
hematocrit
According to Bernoulii’s principle, when a vessel diameter decreases what happens
the velocity increases
___________ can be defined as the physical factors that govern blood flow
Hemodynamics
Ohm’s Law Formula
I=V/R Where I =Current Flow V=Velocity drop R= Resistance
CO =
MAP-CVP/SVR
_____ ______ is the force exerted by the blood against any unit area of the vessel wall
blood pressure
One mm of Hg pressure -
1.36 cm H20 pressure
Blood flow through an organ or any vascular network is driven by a _______ _____ that is normallly represented by the difference between the ____ and ______ pressures across the organ
perfusion pressure / arterial and venous
Cerebral Perfusion Pressure =
MAP-CVP or ICP (whichever is higher)
Coronary Perfusion Pressure =
DBP-LVEDP
Blood flow is directly proportional to thefourth power of the radiusof the vessel, which demonstrates once again that the ________________ plays by far the greatest role of all factors in determining the rate of blood flow through a vessel.
diameter of a blood vessel (which is equal to twice the radius)
Flow is ___________ proportional to the length of the tube
Inversely
In the systemic circulation, about ________ of the total systemic resistance to blood flow is arteriolar resistance in the small arterioles
two-thirds
Flow is ___________ proportional to the viscosity of the tube
Inversely
The greater the ________, the lower the flow in a vessel if all other factors are constant
Viscosity
The viscosity of normal blood is about ____ times the viscosity of water
3 times
If a person has a HCT of 40, this means that _____% of the blood volume is cells and the remainder is plasma
40%
_________ is the impediment to blood flow in a vessel and cannot be measured by any direct means
Resistance
SVR =
(MAP-CVP)/CO x 80
Normal SVR
700-1600
SVR is primarily determined by changes in BLOOD VESSEL DIAMETER, changes in _______ also affect SVR
Viscosity
SVR refers to the resistance to blood flow offered by ALL of the systemic vasculature except the _____ ______
pulmonary vasulature