Cardio Pharm - USMLE RX Flashcards Preview

! Term 5 - Pharm Book > Cardio Pharm - USMLE RX > Flashcards

Flashcards in Cardio Pharm - USMLE RX Deck (22):
1

antiarrhythmic - QT prolongation

Sotalol

2

reduce his blood pressure and slow the damaging effects of diabetes on his renal and cardiovascular systems

ACE inhibitor

3

ACE side effect

Hyperkalemia / myopathy - CYP3A4

4

diltiazem - EKG

Prolongation of the PR interval

5

used as first-line therapy to achieve diuresis in patients with pulmonary edema due to CHF exacerbations.

furosemide

6

most commonly associated with amiodarone toxicity?

Fatigue, weight gain, and constipation are classic signs and symptoms of hypothyroidism

7

Fibrates (etc gemfibrozil) side effect?

Cholesterol gallstones and Myoglobinuria

8

Niacin side effect

Hyperglycemia, Hyperuricemia

9

What causes peaked T waves and widened PR intervals. Name a drug

Hyperkalemia - Spironolactone

10

Drug that blocks α1-, α2-, and β1-receptors.

Labetalol

11

Fibrates act via

Fibrates stimulate synthesis of lipoprotein lipase by activation of the PPAR-α protein. In turn, lipoprotein lipase increases hydrolysis of triglycerides and VLDL, which ultimately results in decreased triglyceride and LDL levels

Peroxisome proliferator-activated receptors

12

Niacin decreases? Increases? (Specifically for lipid levels)

Reduced hepatic triglyceride and VLDL synthesis. Increase HDL

13

How does Adenosine stop AV arrhythmias?

Adenosine works by hyperpolarizing AV node tissue by increasing the conductance of potassium and by reducing calcium current.

14

Treat hypotension due to septic shock

Norepinephrine

15

an antiarrhythmic agent known to cause drug-induced lupus

Procainamide

16

COX 2 inhibitor decreases?

Decreases PGI2, TXA2 normal

17

Digoxin and furosemide

may induce a life-threatening arrhythmia

18

Angioedema - side effect of

ACE inhibitor

19

What is a common heart physiologic effect of norepinephrine?

Decrease in heart rate

20

Common side effects - Thiazides

hyperGLUC (Glycemia, Lipidemia, Uric acid, Calcium.)

21

β-Blockers work by 

inhibiting the G-protein/cyclic adenosine monophosphate (cAMP) mechanism. β-Blockers cause a decrease in Na+ and Ca2+ currents

22

Among antihypertensive agents, the only widely available transdermal (or "patch") medication for lowering blood pressure is

clonidine