Define the measurements of orthostatic vitals that define orthostasis/postural hypotension
Between supine and sitting and/or standing
>15 bpm HR increase suggests depleted circulating blood volume
Primary (essential) HTN casues ____% of elevated BP cases
95%
What are the BP ranges for:

List some causes of secondary HTN
Nonpharmacologic therapies for essential HTN
Dietary Approaches to Stop Hypertension (DASH) diet
weight loss
aerobic exercise
cessation of smoking
What 3 HTN medications are safe during pregnancy?
Methyldopa
Nifedipine
Labetalol
2 major factors that affect BP
CO and PVR
? x ? = Cardiac Output (CO)
HR x SV = CO
HR x SV = CO
What 3 things affect stroke volume (SV)?
Preload
Afterload
Contractility
“-prils” drug class
ACE Inhibitors
Captopril
Enalapril
Lisinopril
“-sartans” drug class
ARBs (Angiotensin II Receptor Blockers)
Losartan
Valsartan
Candesartan
Spironolactone drug class
Aldosterone Antagonist
HTN first line drug for pts with DM and/or CKD
ACEI
ACEI Contraindications
Bilateral renal stenosis
Pregnancy
H/O angioedema
Avoid combining ACEI with what other medications/supplements? Why?
ACEI decrease amount of aldosterone. Aldosterone holds the Na and spits out the K. With decreased levels, less K is spit out and puts pt at risk of hyperkalemia.
Side effects of ACEI
hypotension
renal dysfunction
hyperkalemia
cough
angioedema
ACEI and ARBs relax the _____ arterioles of the nephrons
efferent arterioles
HTN in Special Populations - Which drug(s) would you prescribe?
Thiazide
Thiazide-like diuretics
CCB
HTN in Special Populations - Which drug(s) would you prescribe?
ACEI/ARBs
Thiazide-like diuretics
CCB
HTN in Special Populations - Which drug(s) would you prescribe?
BB
Non-DHP CCB
ACEI/ARB
HTN in Special Populations - Which drug(s) would you prescribe?
ACEI/ARBs
Diuretics
BB
Aldosterone Antagonist
HTN in Special Populations - Which drug(s) would you prescribe?
ACEI/ARB
CCB
HTN in Special Populations - Which drug(s) would you prescribe?
CCB
alpha-blockers
HTN in Special Populations - Which drug(s) would you prescribe?
alpha-blockers