Cardiopulmonary Pharmacology Flashcards Preview

Cardio Pulm > Cardiopulmonary Pharmacology > Flashcards

Flashcards in Cardiopulmonary Pharmacology Deck (21):
1

Types of Adrenergic receptors

-Beta1
-Beta2
-Alpha1
-Alpha2

2

Adrenergic Receptors

-Released by post ganglionic sympathetic neurons
-Types (B1, B2, A1, A2)
-Neurotransmitters (NE, E)

3

Adrenergic Neurotransmitters

-Norepinephrine
-Epinephrine

4

Nicotinic Receptors

-post ganglionic neuron transmission
-muscle contraction

5

2 Cholinergic Receptors

-muscarinic
-nicotinic

6

Muscarinic Receptors cause:

-decrease HR (SA, AV & atria)

7

Anti-Anginal Drugs Work by:

-decreasing myocaridal oxygen demand
-increasing myocardial oxygen supply

8

Beta Blocker Endings

-olol

9

S=

-Selective

(Beta1 receptor only)

10

NS=

Nonselective

(beta1 and beta2 receptors)

11

Alpha1

-many target organs (blood vessels)
-smooth muscle contraction
-increases force of heart contraction

12

Alpha2

-many target organs
-contracts some smooth muscle
-presynaptic of NE release
-inhibition of lipolysis

13

Beta1

-acts on Heart and fat cells
-increases HR
-incr force of heart contraction
-increase lipolysis

14

Beta2

-on smooth muscle and ducts
-Smooth muscle relaxation
-K+ uptake (skel Mm)
-glycogenolysis (liver)

15

Pharmacological Management

-anti-anginals
-heart failure drugs
-antiarrhythmias
-vasopressors

16

2 Positive Inotropes

-cardiac glycosides
-sympathomimetics

17

8 Hypertensive Drug Types

-diuretics
-noradrenergics
-alpha adrenergic blockers
-centrally acting agents
-ACE inhibitors
-Beta blockers
-Ca++ channel blockers
-Angiotensin II receptor blockers

18

-Antiarrythmics

-Class I: Na+ channel blockers
-Class II: Beta blockers
-Class III: prolong repolarization
-Class IV: Ca++ channel blockers
-Digitalis

19

6 Anti-Anginal Drugs

-Beta blockers
-Nitrates
-Ca++ channel blockers
-Thrombolytics
-Antiplatelets
-Anticoagulants

(Beta blockers & Nitrates decrease O2 demand; rest increase O2 supply)

20

6 Heart Failure Drugs

-diuretics
-positive inotropes
-ACE inhibitors
-vasodilators
-beta blockers
-morphine

21

5 Vasopressors

-Isopeterenol
-dopamin
-dobutamine
-epinephrine
-NE (Levofed)