drug cats for HF
4
- diuretics
- cardiac glycosides
- sympathomimetics
- phosphodiesterase inhibitors
3 types of diuretics that support tx of HF
- thiazide
- potassium sparing
- loop
thiazide diuretics therap uses
4
- HF
- HTN
- cirrhosis of liver
- renal failure
diuretic that tx cirrhosis of liver, renal failure
thiazide
thiazide rx ex
2
- hydrochlorothiazide
2. chlorothiazide
thiazide acts where
on proximal portion of distal tubule
thiazide increases excretion of
4
water
sodium
chloride
K
thiazide s/e
4
- fluid and electrolyte imbalances
- dehydration
- hyperglycemia
- hyperuricemia
loop diuretics therap uses
4
- pulmonary edema
- HF
- edema
- HTN
loop increases excretion of
4
- sodium
- chloride
- water
- K
loop s/e
6
- electrolyte imbalances
- hypotension
- dehydration
- ototoxicity
- hyperglycemia
- hyperuricemia
K sparing diur. therap uses
5
- HTN
- edema caused by HF
- cirrhosis of liver
- nephrotic syndrome
- hypokalemia
K sparing diur. rx ex
3
- spironolactone
- triamterene
- amiloride
spironolocatone is to
K sparing diuretic
K sparing diuretic s/e
4
- hyperkalemia
- menstrual irregularities
- abnormal hair growth
- gynecomastia
cardiac glycoside rx ex
1
digoxin
cardiac glycoside (digoxin) therap use 2
- maintenance for HF
2. cardiac dysrhythmias - a fib, a flutter
maintenance drug for HF and tx certain cardiac dysrhythmias
cardiac glycoside (digoxin)
cardiac glycoside (digoxin) s/e 5
- GI upset
- headache
- vision changes
- yellow vision
- cardiac dys.
sympathomimetics (dopamine) therap use
increase CO in severe HF
sympathomimetics (dopamine) pharm action
2
- increase cardiac contraction
2. increase CO
sympathomimetics (dopamine) s/e
3
- tachycardia
- cardiac dys.
- possible angina
two cats of drugs that support the tx of CHD
antilipemics
antianginals
two types of antilipemics
- hmg-coa reductase inhibitors/statins
2. fibrates
statins therap use
3
- reduce LDL
- increase HDL
- reduce risk of heart attack
reduce LDL, increase HDL
statins
statins s/e
3
- myopathy
- rhabdo
- liver toxicity
statins - monitor what is muscle pain occurs
CPK
statins - watch what organ, report impairments
liver
fibrates therap uses
2
- reduce high level of plasma triglycerides
2. reduce LDL
fibrates rx ex
2
- gemfibrozil
2. fenofibrate
fibrates s/e
- GI upset
- gallstones
- myopathy
- liver toxicity
s/e = gallstones
fibrates