Cardiovascular Effects Flashcards Preview

Apex 4 - 5 Volatile Anesthetics II: Pharmacodynamics (11) > Cardiovascular Effects > Flashcards

Flashcards in Cardiovascular Effects Deck (82)
Loading flashcards...
1

Regarding the modern halogenated anesthetics in the adult at 1 MAC:

Study on!!!!

2

In cardiac muscle and vascular smooth muscle, volatile anesthetics ----- Ca+2 influx through the sarcolemma 

"decrease"

3

In cardiac muscle and vascular smooth muscle, volatile anesthetics "decrease" Ca+2 influx through the sarcolemma and ----- Ca+2 release from the sarcoplasmic reticulum

"reduce"

4

Volatile anesthetics also ----- nitric oxide release
 

"modulate"

5

Volatile anesthetics also modulate nitric oxide release, + ----- Ach-induced vasodilation

"inhibit"

6

Volatile anesthetics also modulate nitric oxide release, inhibit Ach-induced vasodilation, and ----- the Na+/Ca+2 pump

 

 

"impair"

7

Volatile anesthetics also modulate nitric oxide release, inhibit Ach-induced vasodilation, and impair the Na+/Ca+2 pump, which ----- intracellular Ca+ 2 concentration.

"decreases"

8

Desflurane ----- Heart Rate

 

"Increases"

9

Nitrous Oxide ----- Heart Rate

 

 

"Increases"

10

Sevoflurane ----- Heart Rate

 

"Has No effect"

11

Isoflurane ----- Heart Rate

 

"Increases"

12

Xenon ----- Heart Rate

 

"Decreases"

13

Desflurane ----- Blood Pressure

 

"Decreases"

14

Nitrous Oxide ----- Blood Pressure

 

"Has No effet" or "Increases"

15

Sevoflurane ----- Blood Pressure

 

"Decreases"

16

Isoflurane ----- Blood Pressure

 

"Decreases"

(significantly!!)

17

Xenon ----- Blood Pressure

 

"Has No effect"

18

Desflurane ----- Cardiac Output

 

"Has No effect" or "Decreases"

19

Nitrous Oxide ----- Cardiac Output

 

"Decreases"

20

Sevoflurane ----- Cardiac Output

 

"Has No effect" or "Decreases"

21

Isoflurane ----- Cardiac Output

 

"Decreases"

22

Xenon ----- Cardiac Output

 

"Nas No effect"

23

Desflurane ----- SVR

 

"Decreases"

24

Nitrous Oxide ----- SVR

 

"Increases"

25

Sevoflurane ----- SVR

 

"Decreases"

26

Isoflurane ----- SVR

 

"Decreases"

27

Xenon ----- SVR

 

"Has No effect"

28

The halogenated anesthetics ----- MAP in a dose-dependent fashion

"decrease"

29

The halogenated anesthetics decrease MAP in a dose-dependent fashion. At equivalent doses, there is ----- between agents

"little difference"

30

The halogenated anesthetics decrease MAP in a dose-dependent fashion. At equivalent doses, there is little difference between agents. The Primary Cause: Decreased intracellular Ca+2 in the -----.

Vascular smooth muscle