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Pharmacy Practice V > Cardiovascular Indication and Dosing > Flashcards

Cardiovascular Indication and Dosing Flashcards

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1
Q

What is the dosing of Lopressor for CAD/AFib?

A

BID

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2
Q

What is the dosing of Toprol XL for HFrEF?

A

Start: 12.5 QD
Target: 200 QD

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3
Q

How often do you titrate Toprol XL for HFrEF?

A

Double dose every 2 weeks until you reach the highest tolerated amount

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4
Q

What is the dosing of Zebeta for HFrEF?

A

Start: 1.24 QD
Target: 10 QD

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5
Q

How often do you titrate Zebeta for HFrEF?

A

Double the dose every 2 weeks until you reach the highest tolerated amount

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6
Q

What is the initial dosing of Coreg for HFrEF?

A

Start: 3.125 BID

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7
Q

What is the target dosing of Coreg for HFrEF?

A

<85 kg = 25 BID
>85 kg = 50 BID

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8
Q

What is the counseling of Coreg for HFrEF?

A

Take with food to avoid orthostasis

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9
Q

What is the dosing of Coreg SR for HFrEF?

A

Start: 10 QD
Target: 80 QD

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10
Q

How often do you titrate Coreg/SR for HFrEF?

A

Titrate the dose every 2 weeks until you reach the highest tolerated amount

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11
Q

What is the dosing of Lanoxin Tablets for HFrEF/AFib with Flutter?

A

0.125 - 0.25 QD

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12
Q

Do you give a loading dose of Lanoxin Tablets?

A

Yes in AFib, then it is reduced to 0.125-0.25 maintenance dosing range

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13
Q

What is the dosing of Isosorbide Dinitrate for Chronic Angina?

A

TID

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14
Q

What times do you dose Isosorbide Dinitrate for Chronic Angina?

A

7-12-5 for nitrate free intervals

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15
Q

What is the dosing of Isosorbide Dinitrate ER for Chronic Angina?

A

BID

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16
Q

What times do you dose Isosorbide Dinitrate ER for Chronic Angina?

A

8-2 for nitrate free interval

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17
Q

What is the dosing of Imdur for Chronic Angina?

A

QD

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18
Q

When do you dose Imdur for Chronic Angina?

A

AM

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19
Q

What is the dosing of Nitrostat for Angina?

A

SL tablet, Q5 min up to 3 doses prn

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20
Q

What is the dosing of Apresoline for HTN?

A

BID - QID

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21
Q

What is the concern with Apresoline?

A

Doses >200 mg/day may high higher risk of lupus like reactions

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22
Q

What is the dosing of Plavix for ACS?

A

75 QD

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23
Q

What is Brillinta dosed for and its caution?

A

ACS, use with ASA doses no greater than 75-100 mg QD

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24
Q

What is Pletal dosed for and its caution?

A

Intermittent Claudication, 2-12 wk trial (up to 12 wk for max effect), AVOID grapefruit

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25
What is the dosing of Coumadin for AFib or VTE?
2-10 mg QD
26
What is the dosing of Pradaxa for DVT/PE Prevention and Treatment?
BID
27
What is the caution of Pradaxa for DVT/PE Prevention and Treatment?
Initiated after 5-10 days of parental anticoagulant, AVOID if CrCl <30
28
What is the dosing of Pradaxa for Stroke Prevention in Nonvalvular AFib?
BID
29
What is the caution of Pradaxa for Stroke in Nonvalvular AFib?
Dose adjust if CrCl 15-30, AVOID if <15
30
What is the dosing of Xarelto for DVT/PE Prevention and Joint Replacement?
10 QD
31
What is the caution of Xarelto for DVT/PE Prevention?
AVOID if CrCl <30
32
What is the dosing of Xarelto for DVT/PE Treatment?
15 BID x 21 days 20 QD after
33
What is the caution for Xarelto for DVT/PE Treatment?
Take with food for doses >15mg AVOID if CrCl <30
34
What is the dosing of Xarelto for Stroke Prevention in Nonvalvular AFib?
20 QD with evening meal
35
What is the caution of Xarelto for Stroke Prevention in AFib?
Dose adjust if CrCl 15-50 AVOID if <15
36
What is the dosing of Eliquis in DVT/PE Prevention and Joint Replacement?
2.5 mg BID Begin 12-24 hrs post op
37
What is the therapy duration for Joint Replacement?
HIP = 35 days KNEE = 12 days
38
What is the dosing of Eliquis for DVT/PE Treatment?
10 mg BID x 7 days 5 BID after
39
What is the duration of Eliquis for DVT/PE Treatment?
2.5 BID for 6 MONTHS
40
What is the dosing of Eliquis for Stroke Prevention in Nonvalvular AFib?
5 BID
41
What is the caution of Eliquis for Stroke in AFib?
Reduce to 2.5 BID if any 2 of the following are present: 1. >80 yrs 2. Weight <60kg 3. Serum Creatinine >1.5 May Consider if CrCl <15
42
What is the dosing of Savaysa for DVT/PE Treatment?
QD
43
What is the caution of Savaysa for DVT/PE Treatment?
Initiate after 5-10 days of parenteral anticoagulant Reduce dose if <60 kg Dose adjust if CrCl 15-50 AVOID <15
44
What is the dosing of Savaysa for Stroke Prevention in AFib?
QD
45
What is the caution of Savaysa for Stroke Prevention in AFib?
Dose adjust if CrCl 15-50 AVOID if <15 or >95
46
What is Zaroxolyn dosed for and its caution?
Edema due to CHF, used as 2nd diuretic sometimes dosed every other day
47
What is the dosing of Aldactone for HFrEF?
Start: 12.5 QD Target: 25 QD
48
What is the caution of Aldactone for HFrEF?
AVOID CrCl <30
49
What is the dosing of Inspra for HFrEF POST MI?
Start: 25 QD Target: 50 QD
50
What is the dosing of Corlanor for HFrEF with EF <35%?
Start: 2.5-5 BID Target: 7.5 BID
51
Why use Corlanor for HFrEF with EF <35% and what is its titration criteria?
To decrease hospitalizations and titrate HR 50-60 bpm
52
What is the dosing of Entresto for HFrEF?
Start: 24/26 BID Target: 97/103 BID
53
What is the caution for Entresto for HFrEF?
Reduce dose if eGFR >30
54
What is the dosing of Altace for HFrEF?
Start: 1.25 - 2.5 QD Target: 10 QD
55
What is the dosing of Capoten for HFrEF?
Start: 12.5 - 25 BID/TID Target: 50 TID
56
What is the dosing of Vasotec for HFrEF?
Start: 2.5 BID Target: 10-20 BID
57
What is the dosing of Zestril for HFrEF?
Start: 2.5-5 QD Target: 40 QD
58
When can you dose Zestril BID?
HTN
59
What is the dosing of Atacand for HFrEF?
Start: 4-8 QD Target: 32 QD
60
What is the dosing of Cozaar for HFrEF?
Start: 25-50 QD Target: 150 QD
61
What is the caution of Cozaar for HFrEF?
Lower initial dose in hepatic disease
62
What is the dosing of Diovan for HFrEF?
Start: 20-40 BID Target: 160 BID
63
What is the dosing of Norvasc for HTN?
2.5-10 QD
64
What is the dosing of Norvasc for Vasopastic/Chronic Stable Angina?
5-10 QD
65
When do titrate dosing for Cardura in HTN?
Titrate Q1-2 wks, re-titrate to avoid syncope
66
When do you titrate dosing for Hytrin in HTN?
Re-titrate if therapy interrupted
67
What is the dosing of Catapres for HTN?
0.2 - 0.6 QD in 2 divided doses
68
When do you titrate Catapres for HTN?
Initial dose of 0.1 BID, can increase to 0.1 mg/day increments at weekly intervals
69
What is the dosing of Catapres TTS for HTN?
0.1 - 0.3 mg/day patch applied every 7 days
70
What is the caution of Catapres TTS for HTN?
Onset delayed 2-3 days after intiation
71
When should you titrate Mevacor, Pravachol, and Zocor for Dyslipdemia/ACS Prevention?
Titrate Q 4-6 weeks; dose with evening meal
72
What statin has a 80 mg/day dosage restriction?
Zocor
73
What is the patient counseling of Lopid for Hypertriglycerdemia >500?
Take on empty stomach 30 mins before morning and evening meals
74
What is the dose of Tricor for Hypertriglycerdemia >500?
48-145 QD
75
What is the caution of Tricor for Hypertriglycerdemia >500?
CI if CrCl <30
76
What is the caution of Trilipix for Hypertriglycerdemia >500?
CI if CrCl <30
77
What is the titration schedule of Question for Hypertriglycerdemia LDL Lowering?
Titrate Q 4-6 weeks
78
What is the dosing of Niaspan for Hypertriglycerdemia >500?
500 - 2000 mg Q HS with snack
79
What is the titration of Niapsan for Hypertriglycerdemia >500?
Extended Release; titrate 500 mg Q4 weeks to response
80
What is the dosing for Zetia for Hypertriglycerdemia LDL Lowering
10 QD
81
When do you take Vytorin for Hypertriglycerdemia LDL Lowering
Taken in the evening
82
What is the dosing for Lovaza for Hypertriglycerdemia >500?
4 caps QD or 2 caps BID
83
What is the counseling for Lovaza for Hypertriglycerdemia >500?
1 cap = 1 g, take with food
84
What is the dosing of Cordarone for AFib?
100-200 QD

Pharmacy Practice V (19 decks)

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