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Flashcards in Cells & Signalling Deck (21):
1

Interneurones

Generally inhibitory (reduce excitory activity of principle cells), use GABA as neuro transmitter

2

Glia

Control neuronal growth & regenerate damaged tissue by providing structural & chemical signals

3

Glial cell types

Astrocytes, ependyma, microglia, oligodendriglia, Schwann cells

4

Astrocytes

Bridge layer between blood vessels and neurones (BBB), modulate neuronal transmission (endocytosis)

5

Ependyma

form sheets to line ventricular system, produce & transport CSF

6

Microglia

activated by trauma, CNS macrophage equivalent

7

Oligodendroma & Schwann cells

Produce myelin sheath
Schwann cells: PNS, oligodendroma: CNS

8

Synaptic plasticity

Synapses altering how they respond to stimulation, allows learning and memory formation.
Rich in the hippocampus

9

CNS inhibitory neurotransmitter

GABA

10

CNS excitory neurotransmitter

glutamate

11

PNS somatic & autonomic neurotransmitter

acetylcholine

12

PNS autonomic only neurotransmitter

noradrenaline

13

Neurotransmitter imbalance in Parkinson’s

reduced dopamine production

14

Huntington’s neurotransmitter imbalance

reduced GABA & acetylcholine levels

15

Neurotransmitter imbalance in Myasthenia Gravis

reduced acetylcholine receptivity

16

Neurotransmitter imbalance in migraine

increased serotonin levels

17

Neurotransmitter imbalance in fibromyalgia

increased substance P or serotonin levels

18

Neurotransmitter imbalance in Alzheimer’s disease

reduced acetylcholine production

19

Neurotransmitter imbalance in Schizophrenia

increased dopamine production

20

Neurotransmitter imbalance in depression

reduced serotonin or noradrenaline levels

21

Neurotransmitter imbalance in epilepsy

reduced GABA levels