Cellular Adaptions Flashcards Preview

Pathology -- Gen Path > Cellular Adaptions > Flashcards

Flashcards in Cellular Adaptions Deck (17):
1

Examples of when insoluble signals might be used

1. Anchoring to stromal elements (ECM)
2. Anchoring to other parenchymal cells and organizing components (BM)
3. Adherence to adjacent, migrating cells
4. Adhesion molecules give signaling + Anchorage

2

What are labile cells?

Divide Continuously

3

Examples of labile cells

Skin/Hair, GI, and Resp. Epithelial Cells, Stem Cells

4

What are quiescent or stable?

Cells that divide only in situation of stress or repair

5

Examples of quiescent tissues?

glandular tissues, liver cells, stromal cells, smooth muscle cells, endothelial cells, renal tubular epithelium

6

Examples of cells that don't divide in adulthood

Cardiac muscle, skeletal muscle, nerve cells

7

Examples of physiologic hypertrophy

Increased muscle mass with exercise, growth factors, hormonal activity (uterus in pregnancy)

8

Examples of physiologic hyperplasia

Growth under normal hormonal control (lactation, menstrual cycle, puberty)

9

Examples of pathologic hypertrophy

Abberant hormone secretion, cancers

10

What is compensatory hyperplasia?

Replacement of lost tissue due to resection or necrosis (cell death), allowing cell proliferation to occur, but not increasing the overall size of the tissue.

11

What is atrophy?

Reduced size of organ or tissue from a decrease in cell size.

12

What is apoptosis?

Loss of cells through programmed cell death

13

What is hypoplasia?

Too little division -- developmental defect in which a tissue fails to develop to normal size due to tissue failure to divide

14

What is aplasia?

Developmental defect in which a tissue fails to develop at all due to absence of a primordium

15

What is metaplasia?

Reversible change in which one adult cell type is replaced by another adult cell type.
Usually an adaptive response to chronic stress.

16

What is dysplasia?

A disordering of the tissue architecture characterized by loss in the uniformity of the individual cells as well as a loss of their architectural orientation.

17

What is neoplasia?

An uncontrolled growth of tissue in the form of a tissue mass.