Cellular Respiration Part 1 Flashcards Preview

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Flashcards in Cellular Respiration Part 1 Deck (22):
1

Where does Glycolysis happen in the cell?

In the Cytoplasm

2

Does Glycolysis use oxygen?

No

3

What is overall happening in cellular respiration?

Glucose is being oxidized to Carbon Dioxide,

While Oxygen is being reduced to Water

4

What is the most universally prevalent process in cellular respiration that occurs in ALL organisms?

Glycolysis

5

In step 1 of Glyolysis,

PHOSHORYLATE glucose

HEXOKINASE adds a phosphate group to Glucose in order to create Glucose 6 -P
1 ATP USED

6

In step 2 of Glycolysis.

Create an ISOMER of Glucose 6-P via

Glucose -6 -P is turned into Fructose -6 -P via an isomerase

7

In step 3 of Glycolisis,

PHOSPHORYLATE Fructose 6-P
to create P-Fructose-P (Fructose 1,6 Bisphosphate)

Enzyme Used: PHOSPHOFRUCTOKINASE
1 ATP used

8

In Step 4 of Glycolysis

Frcutose 1, 6 BisP is broken into two GAP (glyceraldehyde -3 -P molecules)

9

In Step 5 of Glycolysis

GAP is turned into PEP (phosphoenolpyruvate)
4 ATP GAINED
2 NADH GAINED

10

In Step 6 of Glycolysis

PEP is turned into Pyruvate via PYRUVATE KINASE

11

What are the regulatory point of glycolysis?

Glucose 6-P has negative feed back on hexokinase

ATP has negative regulation on Phophofructokinase

12

What is the point of no return for the glycolysis?

When Fructose 6 Phosphate turns into Fructose 1,6 Bisphosphatase

13

What are other fates of Glucose 6-P other than glycolysis?

1) Pentose Phosphate Pathway
2) It can be turned back into glucose and released into the bloodstream

14

Where does the PDC/Kreb's cycle take place?

The mitochondrial matrix

15

Do you need oxygen for PDC/Kreb's cycle?

Yes, you do use it, but it is used indirectly

16

What are the components of mitochondria

From outer most to innermost:
1) Outermost Membrane
2) Intermembrane space
3) Inner Mitochondrial membrane
4) Mitochondrial matrix

17

Where do the pyruvate from the cytoplasm go to in order to continue PDC/Kreb's Cycle?

They enter the matrix of the mitochondria

18

What are the overall reactants and products of of PDC step?

PDC Reactants, products:
Reactants: 2 pyruvate
Products : 2 Acetyl Co-A, 2NADH, 2CO2

19

What are the overall products and reactants for the Kreb's Cycle?

Kreb's Cycle Reactants and Products

Kreb's Cycle is not purely a Reactants vs. Products Equation, it is a cycle.

Steps:
1) Oxaloacetate (4C) + Acetyl CoA (2C)
2) 6C/Citrate
3) 6C-5C (+NADH, CO2 released)
4) 5C-4C ( +NADH, CO2 released)
5) 4C-4C (+GTP,. +NADH, +FADH2)


20

After the PDC/Kreb's cycle and Glycolysis, what is the overall numbers of NADH, FADH, GTP there are that will go into the Electron Transport chain and Oxidative Phosphorylation per Glucose molecule?

How much ATP does this constitute to?

There is a total of
From Glycolysis: 2 NADH
From PDC: 2 NADH gained
From Kreb's Cycle: 6 NADH, 2 FADH2

Total: 10 NADH, 2 FADH2 gained

2 NADH from Glycolysis: 3 ATP
8 NADH from PDC+ Kreb's Cycle: 20 ATP
2 FADH2 from Kreb's Cycle: `3 ATP

2 ATP from Glycolycis+ 2 GTP from Kreb's Cycle: 4 ATP

30 ATP total

21

What are the 5 Transmembrane proteins involved in the Electron transport chain?

1) NADH Dehydrogenase
2) CO Q
3) Cytochrome C
4) Cyt C oxidase
5) Lastly, there is a proton pump that couples H+ moving down gradient back to mitochondrial matrix with ATP generation

This is where the 10 NADH and 2 FADH2's "energy" is turned into 26 ATP


22

What is the other use of the Glucose 6-P that is essential for the body? Why is this essential? Where does this alternate use of Glucose - 6 -P occur?

Glucose-6 -P can go through the Pentose-Phosphate Pathway. The Pentose-Phosphate pathway is important it helps to generate NADPH, which helps to reduce free radicals, which can cause cellular damage. (Oxidative phase)

It also helps to create Ribose 5 -Phosphate, necessary for DNA synthesis.
Also makes intermediates for glycolysis