Flashcards in Cephalosporins Deck (41)
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Cephalosporins not active against
L. monocytogenes
Enterococci
1
T/F each succeeding generation is more effective against g negative bacteria and broader spectrum of activity
T, 4th gen has broadest spectrum
2
Cefazolin
1st gen
3
Cephalothin
1
4
Cephalexin
1
5
Cephradine
1
6
Cefadroxil
1
7
Cefaclor
2
8
Cefamandole
2
9
Cefonicid
2
10
Cefuroxime
2
11
Cefprozil
2
12
Loracarbef
2
13
Ceforanide
2
14
Cefixime
3
15
Moxalactam
3
16
Ceftriaxone
3
17
Cefotaxime
3
18
Cefepime
4
19
Gram positive cocci
Pneumococci
Streptococci
Staphylococci
20
Cross allergenicity more common compared to other generations
1st
21
The only first gen cephalosporin still in use
Cefazolin
22
2nd gen extension, organisms?
Klebsiella
H. influenza
B. fragilis
M. catarrhalis
N. gonorrhea
N. meningitides
23
2nd gen cephalosporin that can cross the BBB
Cefuroxime
24
3rd gen with useful activity against P. aeruginosa
Ceftazidime
Cefoperazone
25
Used as empirical therapy of sepsis of unknown cause in immunocompromised and immunocompetent patients
3rd gen cephalosporins
26
Reduced effects against staph but same activity against strep
Ceftriaxone
27
Iv/im cns and genitourinary infections
Bone and joint infections
Skin and soft tissue infections
Mild community acquired respiratory infections
Ceftriaxone
28
Adverse effect: biliary sludge
Ceftriaxone
29
