Cephalosporins Flashcards Preview

Ther 201 3rd Exam > Cephalosporins > Flashcards

Flashcards in Cephalosporins Deck (41)
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Cephalosporins not active against

L. monocytogenes
Enterococci

1

T/F each succeeding generation is more effective against g negative bacteria and broader spectrum of activity

T, 4th gen has broadest spectrum

2

Cefazolin

1st gen

3

Cephalothin

1

4

Cephalexin

1

5

Cephradine

1

6

Cefadroxil

1

7

Cefaclor

2

8

Cefamandole

2

9

Cefonicid

2

10

Cefuroxime

2

11

Cefprozil

2

12

Loracarbef

2

13

Ceforanide

2

14

Cefixime

3

15

Moxalactam

3

16

Ceftriaxone

3

17

Cefotaxime

3

18

Cefepime

4

19

Gram positive cocci

Pneumococci
Streptococci
Staphylococci

20

Cross allergenicity more common compared to other generations

1st

21

The only first gen cephalosporin still in use

Cefazolin

22

2nd gen extension, organisms?

Klebsiella
H. influenza
B. fragilis
M. catarrhalis
N. gonorrhea
N. meningitides

23

2nd gen cephalosporin that can cross the BBB

Cefuroxime

24

3rd gen with useful activity against P. aeruginosa

Ceftazidime
Cefoperazone

25

Used as empirical therapy of sepsis of unknown cause in immunocompromised and immunocompetent patients

3rd gen cephalosporins

26

Reduced effects against staph but same activity against strep

Ceftriaxone

27

Iv/im cns and genitourinary infections
Bone and joint infections
Skin and soft tissue infections
Mild community acquired respiratory infections

Ceftriaxone

28

Adverse effect: biliary sludge

Ceftriaxone

29

Has longest half life among 3rd gen

Ceftriaxone