Ch 10 Flashcards Preview

immunology > Ch 10 > Flashcards

Flashcards in Ch 10 Deck (14):
1

gp120

viral attachment protein HIV

2

gp41

involve w/ fusion with cell HIV

3

p24

nucleocapsid of HIV

4

p17

nitrous protein HIV

5

p64

reverse transcriptase HIV

6

HIV genome

diploid ssRNA

7

compromised T cell and B cell activation

SCID

8

X-linked
purines not degraded
inhibits new purines
dATP accumulates

adenosine deaminase ADA

9

X linked
defective WASP gene

Wiskott-Aldrich Syndrome

10

no B cells
loss of Btk tyrosine kinase

X-linked agamma-globulinemia

11

genes that make someone HIV immune

CCR5 and CXCR4

12

less than 500 CD4

ARC

13

less than 200 CD4

AIDS

14

antivirals for HIV

protease inhibitors
reverse transcriptase inhibitors
entry/fusion inhibitors