CH 16-1 Flashcards Preview

BIO 119-352 > CH 16-1 > Flashcards

Flashcards in CH 16-1 Deck (30):
1

filters lymph fluid; where lymphocytes meet each other & their antigens

lymph nodes

2

2. site of hematopoiesis

bone marrow

3

3. glycoprotein receptors on all nucleated cells; presents endogenous antigens; recognized by CD8 Tc cell

MHC I

4

4. glycoprotein receptors on APCs, present exogenous antigens

MHC II

5

T cells mature here

thymus

6

6. can present exogenous antigens on both MHC I & II

dendritic cells

7

7. includes challenge & induction of B cell clones, with help of Th2, into plasma cells producing immunoglobulins and memory cells

T dependent humoral immunity

8

8. produced by induced B & T lymphocytes; responds quickly upon seeing antigen again

memory cells

9

attacked by HIV virus; recognizes antigen when presented on MCH II

CD4 helper t cells

10

molecule secreted by activated Tc cells that activates enzymes for apoptosis

granzymes

11

polypeptide with 2 heavy & 2 light chains; is monospecific for epitope; has constant & variable portions

antibody

12

includes activation of Helper T cells; cytotoxic T (Tc) cells killing virally infected, tumor or foreign human cells; memory

cell mediated immunity

13

13. filters blood; B cells finish maturing here

spleen

14

14. crystallizable fragment; class of Ig determined by this; can bind to neutrophils & macrophages

Fc

15

type of antigen that is a part of, or is produced by microbes

exogenous

16

3D portion of antigen recognized by monospecific antibody

epitope

17

can have multiple epitopes; the best are large, complex, foreign & made of proteins

antigen

18

B plasma cells producing antibodies by binding directly to large repeating antigens; weak response & memory

T independent humoral immunity

19

normal cell protein that triggers adaptive immune response, but shouldn’t

autoantigen

20

20. signals like interleukins & chemokines secreted by leukocytes to regulate immune system

cytokines

21

molecule secreted by activated Tc cells that makes a membrane pore

perforins

22

variable portion of heavy & light chains of an antibody

antigen binding site

23

type of antigen that is made inside human cell & presented on MHC I

endogenous

24

acquired when clones recognizing self or autoantigens are destroyed

self tolerance

25

25. body’s surveillance system; includes vessels, lymph, nodes, spleen, thymus, tonsils & Malt

lymphatic system

26

26. infant drinks breast milk

natural passive

27

27. immunoglobulins given for snake venom

artificial passive

28

28. body makes antibodies against normal human protein

autoimmunity

29

29. immunity acquired after recovery from chicken pox

natural active

30

30. patient receives influenza vaccine

artificial active