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Flashcards in Ch 21 Deck (26)
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1

Biological features of Treponema pallidum
-shape
-arrangement
-gram stain(NO)
-motility (motile)
-form of respiration

shape:
arrangement:
Respiration:

NO GRAM STAIN

-has internal flagella
-STRICT PARASITE
Fastidious
-motile
-cannot survive long outside of host

2

Diseases of Treponema pallidum
-Syphilis

(Syphilis)
-Cutentral
-Congenital
Stages: (Primary, secondary, Tertiary)

Primary
-chancre sores
-highly contagious

Secondary
-hair loss
-systemic rashes

Tertiary
-Damages pathological tissues
-gumma development

3

Mechanim of Disease for Treponema pallidum
-virulence factors

(Virulence)
>Outter membrane proteins

4

Transmission of Treponema pallidum
-Method
-Habitat
-Audience
-Resevoir

(Method)
-Sexually
(Habitat)
-oral cavity
-intestinal tract
-perigenal regions of human animals
(Audience)
-Children (congenital syphilis)
-Adults
(Resevoir)

5

Prevention & Treatment of Treponema pallidum

(Prevention)
-detection and treatment of sexual partners
-condoms
(Treatment)
-Penecillin G

6

CURVIFORMS
-Vibrio
-
-

-Gram (-)
-flagellated

7

Biological features of Vibrio Cholera
-shape
-arrangement
-gram stain(-)
-motility (yes)
-form of respiration

(curviform)

shape: vibrio
arrangement:
Gram stain: (-)
Respiration:

-free living
-somatic antigens
-flagella
-fermentative
-strictly epipathogen
-darting motility

8

Disease of Vibrio Cholera
-Asiatic Cholera
symptoms
-Gastroenteritis
symptoms

(Asiatic Cholera)
-shedding of electrolytes in intestine
symptoms:
vommiting, secretory diarrhea-waterly stool
(Gastroenteritis)
symptoms:

9

Mechanim of Disease for Vibrio Cholera
-virulence factors

(Virulence)
>Enterotoxin: Cholera toxin

>Enzyme:
- converts AMP to cAMP
-controls membrane pump. pumps Cl & HCO3 into lumer

10

Transmission of Vibrio Cholera
-Method
-Habitat
-Audience
-Resevoir

(Method)
-Freeliving
-water and food
(Habitat)
-Rests on surface of intestinal mucosa
(Audience)
-
(Resevoir)
-

11

Prevention & Treatment of Vibrio Cholera

(Prevention)
-proper sewage disposal
-water purification

(Treatment)
-water/ electrolyte replacement

not treated with antibiotics

12

Biological features of Campylobacter jejuni Enteritis
-shape
-arrangement
-gram stain(-)
-motility (yes)
-form of respiration

(curviform)

shape: vibrio, curved bacilli
arrangement:
Gram stain: (-)
Respiration:

-polar flagellum
-spinning motility
-microaerophilic & thermophilic
-oxidase (+)
-nonfermenting (???)
-SELF-LIMITING

13

Disease of Campylobacter jejuni Enteritis
-Gastroenteritis
symptoms

(Gastroenteritis)
symptoms:

14

Mechanim of Disease for Campylobacter jejuni Enteritis
-virulence factors

once ingested, C.jejuni travels to mucosa of illeum near colon> disrupts cytoskeleton & damages epithelium & penetrates intestinal wall

(Virulence)
>Heat labile entertoxin (CJT)
-stimulated secretry diarrhea

influx of wbc into intestine

15

Transmission of Campylobacter jejuni Enteritis
-Method
-Habitat
-Audience
-Resevoir

(Method)
-contaminated beverages and food (meat)
(Habitat)
-intestinal tract
-genitourinary tract
-oral cavity
(Audience)
-
(Resevoir)
-

16

Prevention & Treatment of Campylobacter jejuni Enteritis
(is self-limiting)

(Prevention)
-sanitary control
(Treatment)
-rehydration and electrolye therapy

17

Biological features of Helicobacter pylori
-shape
-arrangement
-gram stain(-)
-motility (????)
-form of respiration

(curviform)

shape: vibrio
arrangement:
Gram stain: (-)
Respiration:

-microaerophilic
-oxidase (+)
-multiple sheathes flagella**
-zoonosis
-thrives in acidic environment

18

Disease of Helicobacter pylori
-Gastritis
symptoms

(Gastritis)
symptoms:

(Ulcers)

19

Mechanim of Disease for Helicobacter pylori
-virulence factors

Pathology:
sdfsdgfg

(Virulence)
>flagella
-attatchment
>enzyme: URASE
-convers urea too NH4+ & HCO3-
-neutralizes stomach acid

20

Transmission of Helicobacter pylori
-Method
-Habitat
-Audience
-Resevoir

(Method)
-oral-oral
-fecal-oral
-flies as mechanical vector
(Habitat)
-human stomach (thrives in acidic environ)
(Audience)
-
(Resevoir)
-

21

Prevention & Treatment of Helicobacter pylori

(Treatment)
-
(Prevention)
-

22

Biological features of Chlamydia trachomatis
-shape
-arrangement
-gram stain(NO)
-motility (??????)
-form of respiration

shape:
arrangement:
Respiration:

NO GRAM STAIN

-Intracellular
-obligate parasite (can't be grown atrificially)

23

Disease of Chlamydia trachomatis
-ocular trachoma
-inclusion conjunctivitis
-chlamydiosis
-Non gonococcal urethritis
-Salpingitis (PID)
-lymphogranulomma veriereum

(ocular trachoma)
-
(inclusion conjunctivitis)
-
(chlamydiosis)
-
(Non gonococcal urethriti)
-
(Salpingitis (PID))
-
(lymphogranulomma veriereum)
-

24

Mechanim of Disease for Chlamydia trachomatis
-virulence factors

Pathology:
sdfsdgfg

(Virulence)

25

Transmission of Chlamydia trachomatis
-Method
-Habitat
-Audience
-Resevoir

(Method)
-
(Habitat)
-Squmos & collumnar cells of mucus membranes in eyes, lungs, genitourinary tract
-lymphatic tissues & genetalia
(Audience)
-
(Resevoir)
-

26

Prevention & Chlamydia trachomatis

(Prevention)
-Drug therapy
-condoms
(Treatment)
newborns:
-erythromycin/ doxycycline
urogenital infections:
-doxycycline/ azithromycin