Flashcards in Ch 4 (Exam 1) Deck (87):
Name the two Autonomoic Nervous System Anatomy
Sympathetic Autonomic Nervous System (SANS)
Parasympathetic Autonomic Nervous Systems (PANS)
Cranial nerves and sacral segments of spinal cord are dealing with which Nervous System?
What are the cranial nerves and segments involved with PANS?
Cranial Nerves 3,7, 9 and 10
S2-S4 segments of spinal cord
What cranial nerve is 3?
What is cranial nerve 7?
What cranial nerve is 9?
What cranial nerve is 10?
Where do the pre and post ganglionic neuron meet?
When the pupils are dilated the effect is termed?
When pupils are constructed the effect is termed?
The space between the preganglionic and postganglionic fibers is termed?
Synapse or synaptic cleft
Term for loss of vision?
Adverse reactions of Cholinergic agents
Direct acting - acts like acetylcholine at receptor sites.
Indirecting acting- causes increase in amount of acetylcholine indirectly
Both ANS divisions consist of what fibers?
Afferent (sensory) fibers
Central Integrating Areas
Efferent (peripheral) Motor: preganglinoic and postganglionic motor fibers
Efferent motor nerve consist of both?
Originates in the central Nervous System (CNS) and passes out to form the ganglia at the synapse with the postgaglionic nerve?
Originates in the ganglia and innervates the effector organ or tissue?
Three acetylcholine (AcH) receptor sites?
Side effects of Pilocarpine?
Rhinitis (stuffy nose)
Pilocarpine (salagen) available in what?
5-mg tablets taken tid
Pilocarpine (IsoptoCarpine) used to treat glaucoma, by what route?
T/ F. Pilocarpine also available as ophthalmic solution in strengths ranging from 0.5% to 10%
T/F Cholinergic Agents: are choline esters and act directly to receptor.
Communication between nerves or between nerves and effector tissue takes place by the release of chemical neurotransmitter across the synaptic cleft?
The neurotransmitter connected with PANS ?
The neurotransmitter associated with SANS ?
Effector organs in SANS ?
Effector organs in PANS?
Receptor in PANS?
Receptors in SANS?
T/F Cholinergic Agents: indirect-acting, are cholinesterase inhibitors. They inactivate the enzyme thus permitting AcH to react to the receptor
What are the primary postsynaptic neurotransmitters for the sympathetic nervous system?
Which naturally occurring cholinergic agents is given to stimulate saliva flow?
Which adrenergic drug is used to treat asthma?
Which terms refer to the same groups of medications?
All are adverse reactions of cholinergic agents except which of the following?
Neuromuscular paralysis in large doses Incorrect
The term catecholamine refers to which agents?
In the autonomic nervous system, the preganglionic neuron originates in the __________ and passes out to form the ganglia at the __________ with the postganglionic neuron. The postganglionic neuron originates in the __________ and innervates the __________.
central nervous system, ganglia, synapse, effector organ
The sensory components of ANS are the __________ fibers, and the motor component of the ANS are the __________ fibers.
A drug that acts at the location where norepinephrine is the neurotransmitter released would be termed
A drug that has the suffix __________ has the same action as an agonist.
A drug that acts at the location where a division of the ANS acts and blocks the action (acting as an antagonist) of the neurotransmitter has the suffix __________.
What is the principal neurotransmitter of the PANS?
The action of the released acetylcholine is terminated by hydrolysis by the enzyme
The direct-acting cholinergic or parasympathomimetic (PANS) agents include which drugs?
Which conditions are contraindications for PANS agents?
Severe cardiac disease
Gastrointestinal or urinary tract obstruction
The anticholinergic or parasympatholytic agents are often used therapeutically to treat which conditions?
Decrease salivation and secretions to produce a dry field in oral surgery
Bronchodilator for asthma
Dilation of the pupils for ophthalmologic examinations
The combination of anticholinergic agents and levodopa is sometimes used for the treatment of __________.
Examples of sympathomimetic adrenergic agonists include which drugs?
Produces dry field for oral surgery?
Used in treatment of shock?
OTC cold and allergy medication?
Vasoconstrictor in local anesthetics?
Blocks action of β receptors in SANS?
Treatment of motion sickness?
Treatment of glaucoma?
Used to facilitate intubation for general anesthetic?
Treatment of ADD and ADHD?
The two components of the ANS, the sympathetic autonomic nervous system (SANS) and the parasympathetic autonomic nervous system (PANS) together control regulation of which bodily functions?
Regulation of blood pressure and heart rate and smooth muscles of the gut and bronchi
When the sympathetic autonomic nervous system is stimulated, the __________ releases epinephrine and norepinephrine, acting as a large sympathetic ganglion.
A reaction that is neither a side effect or allergic reaction
Autonomic Nervous System Functions
Regulates BP, heart rate, GI mobility, salivary gland secretions, and bronchial smooth muscles
Preganglionic neurons originate in the
Postganglionic neurons originate in the
Neurotransmitter between the preganglionic and postganglionic nerves:
These nerves are:
Acetylcholine is released:
at the 1st and 2nd synapse in the PANS
1st synapse in the SANS
ANS drugs are divided into 4 groups:
P+ Cholinergic/Parasympathomimetic (Stimulates PANS)
P- Anticholinergic/Parasympatholytic (Blocks PANS)
S+ Adrenergic/Sympathomimetic (Stimulates SANS)
S- Adrenergic blockers/Sympatholytic (Blocks SANS)
agents attach to the nicotine receptor and result in depolarization?
Major Neurotransmitter in SANS
PANS consists of:
Cholinergic agents (Parasympathomimetic)
Anticholinergic agents (Parasympatholytic)
Nicnotinic agonists and antagonists
Adverse Reactions of Anticholinergic Agents
xerostomia, blurred vision, photophobia, tachycardia, fever, urinary and GI stasis, hyperpyrexia, hot/dry flushed skin, CNS excitation
Acetylcholine is stimulated by _____, therefore it is _____ in response
When a person is taking multiple drugs
2.2 pounds =
Acetycholine is the principle mediator in the
Anti Cholinergic agents used to treat?
Motion sickness (Scopilamine)
Contraindications of anti Cholinergic agents
Anticholingeric inhaler used to treat asthma
Completely blocks receptors (Cholinergic)
Prevents the action of ACh at postganglionic endings
Direct acting: acts like ACh at receptor sites
Indirect acting: causes increase in ACh amount indirectly (breaks down ACh)
Cholinergic agents treat?
Contraindications of Cholinergic agents?
GI or Urinary tract obstruction
Severe cardiac disease
Neurotransmitters between pre and postganglionic?