Ch 47 Flashcards
(90 cards)
When does a human embryo begin to show distinctive features?
5 week
Order of embryonic development (frog) (6)
Zygote
Blastula
Gastrula
Tail-bud embryo (frog)
Larval Stage
Adult
What is the definition for Fertilization?
Formation of diploid zygote from haploid egg and sperm
Sperm ____ the protective layer around the egg
Penetrate
What binds to the molecules on the sperm surface?
Receptors on egg surface
What is Polyspermy?
The entry of multiple sperm nuclei into the egg
What prevents polyspermy
Changes at egg surface
What is triggered when the sperm meets the Egg?
Acrosomal Reaction
What releases hydrolytic enzyme that digest material surround the egg?
Acrosome
What causes fast block to polyspermy
Gamete contact depolarizes the egg cell membrane and causes the blockage
Fusion of egg and sperm initiate which reaction? What does it form?
Cortical Reaction
Forms fertilization envelope
What does the fertilization envelope act as
Slow block to polyspermy
Cortical reaction requires?
High concentration of calcium ion in the egg
What is cortical reaction caused by?
Change in Ca concentration
Spread of Ca correlates with appearance of the fertilization envelope
The rise of Ca in cytosol cause increase of what?
Cellular respiration and protein synthesis by the egg cell
When is an egg activated?
With rapid changes of metabolism (inc cell respiration and protein synthesis)
Where are proteins and mRNA needed for activation come from?
Already present in the egg
Because humans have internal fertilization, sperm must travel through ______ to get to the zone of pellucida
follicle cells
Sperm must travel through a layer of follicle cells surrounding the egg to reach?
The zone pellucida
extracellular matrix of egg
Sperm binding triggers?
Cortical Reaction
Time in mammals for the first cell division?
12-36 hours
What follows after fertilization?
Cleavage: period of rapid cell division without growth
Cleavage partitions the cytoplasm of one large cell into many smaller cells called?
Blastomeres
Ball of cells
Blastula