Flashcards in Ch4: Skin, Musculoskeletal, Blood, and Lymph Part II Deck (289)
Infections of joint and bone include? 4
1. Parovirus B19: Developed countries (Slapped cheek)
2. Rubella: Nonvaccinated adults
3. Hep B: HIV-1 and HTLV-1
5 classic childhood viral rashes?
1. Measles: Rubeola
2. German measles: Rubella
4. Fifth disease
5. Chickenpox: Varicella zoster
5 herpes virus of skin?
1. Herpes simplexes 1 and 2
2. Varicella zoster
3. Human herpes virus 6, 7, 8
4 families of viruses of skin?
3 subfamilies of herpesvirus?
Which has short growth cycle?
Which has long?
Members of alpha herpes family? 3
Members of gamma herpes family? 2
Kaposi' sarcoma: HHV-8
Members of beta herpes family? 3
In terms of herpes
Shape of capsule?
Since herpes have a capsule, they have a tegument which contains what?
Enzymes for replication
What determines what cell/tissue, the herpes virus attacks?
What are the viral adhesins of herpesvirus?
What is the primary manifestation of herpesvirus in humans?
Common infections but benign in children
What is the immune response of herpesvirus?
What is the primary treatment of herpesvirus?
Targeting viral DNA polymerase
What main feature do all herpesviruses have?
How do viruses do latency? (2)
1. Make non-encoding transcripts that prevent apoptosis
2. Express proteins during latency
What is state of herpesvirus genomes during latency?
Circular, episomal form separate from host genome
How are herpesviruses spread? 3
What herpesviruses can be be spread without symptoms?
When is VZV transmitted?
Only when patient has varicella or zoster
What is required for HSV spreading?
Most herpesviruses are diagnosed how?
What is used in confirming acute or previous herpesvirus infection?
PCR is used to test what herpesvirus?
How to detect VZV in ski nlesions?
What herpesviruses cause both intranuclear and cytoplasmic inclusions?
What herpesviruses result in only intranuclear inclusions?
HSV 1-2 infection
Can infect what cell types?
Where is it lytic? (2)
Where is it latent?
Most cell types
Mucoepithelial and fibroblasts