chap 25. Flashcards
1
Q
Strong activating
A
-OH, OR, NH2, NR2 (o,p)
2
Q
Mod Activating
A
Anyhdride, o-c=o-r (OP)
3
Q
Weakly activating
A
r groups (op)
4
Q
Weakly deactivating
A
halogens (o,P)
5
Q
moderately deactivating
A
aldehyde, ester (m)
6
Q
Strongly deactivating
A
CN, NO2, SO3H, NR3 (m)
7
Q
trihalogenation
A
(only if strong activating group is present (no catalyst needed)
8
Q
EDG
A
Stabalizes positive
-decreased energy
-faster rxn
9
Q
RXNS of mono and FC
A
-Amine=no rxn
-strong or mod deactivator=no rxn
10
Q
Bulky Groups
A
Block ortho positions to itself
r-c3
amide
11
Q
Disubstituted benzene rxn
A
Stronger activating group directs rxn
-if subs are meta, position in between them is blocked
12
Q
synthesis
A
take time girl
write everything out/how to get each reagent
