Chapt 7 Bone Tissue Flashcards

1
Q

Five basic functions of skeleton

A
  1. Support
  2. Storage
  3. Blood cell formation (hemopoisis)
  4. Protection
  5. Leverage
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2
Q

Diaphysis

A

Tubular shaft of the bone
-walls consist of a layer of solid compact bone

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3
Q

Epiphyses

A

Extended areas at ends of bone
-consists mostly of spongy bone covered in thin layer of compact bone

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4
Q

What’s inside the spaces of spongy bone

A

Red marrow

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5
Q

Metaphyses

A

Areas in between the epiphyses and diaphysis
-represents areas where a long bone can grow in length

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6
Q

Marrow cavity

A

The space within diaphysis that contains yellow marrow in adult long bones

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7
Q

Periosteum

A

Connective tissue covering the surface of the bone
-contains bone forming cells that allow bones to grow in diameter or thickness (osteoprogenitor)
-protects bone

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8
Q

Endosteum

A

Lining of marrow cavity which contains some bone forming cells and some connective tissue

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9
Q

Articular cartilage

A

At ends of long bone, cartilage reduces friction and absorbs shock at the joints

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10
Q

What is bone tissue

A

Supportive connective tissue containing specialized cells and is surrounded by extracellular fluid

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11
Q

What is the bone matrix composed of

A

33% collagen fibers
67% inorganic components (mostly calcium salts)

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12
Q

Calcium salts are mainly:

A

Hydroxyapatite (calcium phosphate and calcium carbonate)

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13
Q

Calcification

A

Process of bone hardening:
Salts are deposited on framework of collagen fibers and crystallize

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14
Q

Osteoprogenitor (osteogenic) cells

A

Unspeciallized stem cells of bone tissue
-it divides to form another stem cell and an osteoblast as daughter cells

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15
Q

Osteoblasts

A

Cells responsible for calcification
-surround themselves in matrix then transform into osteocytes

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16
Q

Osteocytes

A

Mature bone cells
-no longer secrete matrix
-maintain bone metabolism
-can convert back to osteoblasts or osteoprogenitor if damaged to participate in repair

17
Q

Osteoclast

A

Very large cells that function to remove calcium salts and recycle bone matrix
-release acids and enzymes that digest bone matrix as part as normal growth, repair and mineral homeostasis

18
Q

What does compact bone do?

A

-Makes up most of the diaphysis and lies over spongy bone tissue in the epiphyses
-forms a protective layer and gives bone more support and resistance to stress

19
Q

How is compact bone arranged?

A

In units called osteons with very little space between them, each osteon contains osteocytes arranged in layers around the central canal that contains blood vessels

20
Q

Why can’t compact bone be bent?

A

Because osteons are aligned in the same direction along lines of stress

21
Q

Does spongy bone contain osteons?

A

No it consists of trabeculae

22
Q

Trabeculae

A

Irregular honey comb structure of bone tissue making up spongy bone. Surrounds many red marrow filled spaces

23
Q

Where is spongy bone found?

A

Where bones are not heavily stressed, mostly in short, flat, irregular shaped bones

24
Q

What does spongy bone do?

A

Supports and protects red bone marrow (where blood formation occurs)

25
Ossification
Process of bone formation
26
Epiphyseal plates
Areas where bones can increase in length under the influence of human growth and sex hormones
27
What bone is the last bone to stop growing
Clavicle
28
What happens when growth stops?
Epiphyseal plates fade into Epiphyseal lines
29
Bone growth and remodeling at birth to adolescence
More bone is produced than is lost through bone resorption
30
Bone growth and remodeling in young adults
Rates of bone production and resportion are about the same
31
Bone growth and remodeling at middle age to elderly
Bone mass decreases because more bone is resorbed than produced (demineralization)
32
PTH hormone
Realeased from parathyroid glands when blood calcium is low
33
PTH hormone acts to:
1. Stimulates osteoclasts 2. Inhibit osteoblasts 3. Inhibit excretion of calcium in the kidneys 4. Stimulate the formation of calcium
34
When is calcitonin released?
When blood calcium is too high, released from thyroid gland
35
Calcitonin acts to:
1. Inhibit osteoclasts 2. Stimulate osteoblasts
36
Osteoporosis
Weakening of the bones due to decreased deposition of calcium salts -common in elderly
37
Why re woman more at risk for getting osteoporosis?
-they have less bone mass -reproduction hormones contribute to bone decomposition