Chapter 1 - History Flashcards
(34 cards)
1
Q
- Greek philosopher: “individuals who recovered from plague RARELY contracted the disease again”
A
Thucydides
2
Q
- Inhalation of powdered crust from smallpox lesions
A
Chinese
3
Q
- “variolation”
A
Lady Montagu
4
Q
- “vaccination”
A
Edward Jenner
5
Q
- “pasteurization” ; resistance to fresh culture Pasteurella multocida from injection of old cuture
A
Louis Pasteur
6
Q
- Cellular (phagocytic) theory of immunity
A
Elie Metchnikoff
7
Q
- First proof of humoral immunity theory
A
Emil von Behring & Shibasaburo Kitasato
8
Q
- “passive immunization”
A
Emil Roux
9
Q
- Resolved the conflict between cellular and humoral theories
A
Sir Almroth Wright & S.R. Douglas
10
Q
Publisher and doctrine of humoral immunity theory
A
Paul Ehrlich
11
Q
Complement fixation
A
Bordet and Gengou
12
Q
Passive hemagglutination
A
Boyden
13
Q
Plaque formation by immunocompetent cells in agar gel
A
Jerne, Henry, and Nordin
14
Q
Rosette formation
A
Biozzi and Zaalberg
15
Q
Fluorescent-labelled Ag and Ab
A
Coons
16
Q
Radioactive-labelled Ag and Ab
A
Yalow and Berson
17
Q
Enzyme-labelled Ag and Ab
A
Avrameas and Uriel
18
Q
Ring disk test
A
Bechold
19
Q
Used ring disk test in antrhax diagnosis
A
Ascoli
20
Q
Simple diffusion method (quantitation for Ag-Ab complex)
A
Oudin
21
Q
- Double diffusion method (quali)
A
Ouchterlony and Elek
22
Q
- Immunoelectrophoresis analysis in gels
A
GRABAR and WILLIAMS
23
Q
- Quantitative modification of immunoelectrophor
A
RESSLER and LAUREL
24
Q
- “prophylaxis phenomenon” discovery
A
CHARLES RICHET and PAUL PORTER
25
25. “serum sickness”
CLEMENS VON PIRQUET and BELA SCHICK
26
26. Local or systemic vasculitis caused by an initial exposure to endotoxin producing intravascular fibrin thrombi whose clearance results in reticuloendothelial blockade leading to tissue necrosis or hemorrhage
SCHWARTZMAN RXN/PHENOMENON
27
27. Reaginic Abs adhering to tissue cells that can mediate histamine and serotonin release on contact with the allergen
PRAUSNITZ-KUSTNER RXN (Paul and Heinz)
28
28. “histamine is present in mast cells”
RILEY and WEST
29
29. Side chain theory
EHRLICH
30
30. Template theory of antibody formation
FRIEDRICH BREINL and FELIX HAUROWITZ
31
31. Clonal selection theory; human immunodeficiency discovery
NIELS K. JERNE and FRANK MACFARLANE
32
32. HLA on leukocytes
J. DAUSSET and F. RAPAPORT
33
33. Cooperation of B and T cells
H.N. CLAMAN
34
34. Produced hybridoma
C. MILSTEIN and G.J.F. KOHLER
