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PSYCH2800: Drugs & Behaviour > Chapter 10 > Flashcards

Chapter 10 Flashcards

(21 cards)

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1
Q

DEFINE

Opioids

A

A class of psychoatice substances that act on opioid receptors in the CNS

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2
Q

DEFINE

Opiates

A

Opioids that are naturally ocurring; harvested from the Papaver Somniferum (Poppy plants)

Morphine + Codeine

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3
Q

LIST

What are some semsynthetic opioids?

A
  • Heroin, Buprenorphine, hydrocodine, oxycodone
  • Percocet: Oxycodone + acetaminophen
  • Vicodin: Hydrocodine and acetaminophen
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4
Q

LIST

What are some fully synthetic opioids?

A
  • Fetanyl
  • Methadone
  • Tramadol
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5
Q

LIST

What are some natural opioids?

A
  • Morphine
  • codeine
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6
Q

LIST

What are some administration methods for opioids?

A
  • Inhalation (rare in current times)
  • Oral administration (Codeine, methadone)
  • Intravenous (heroin)
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7
Q

EXPLAIN

What are the distribution properties of Opioids?

A
  • Readily cross the blood-brain barrier
  • Differ in lipid solubility
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8
Q

EXPLAIN

What is the metabolism properties of opioids?

A

Most have active metabolites

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9
Q

Explan

The Harrison Act (1914)

A

restricts opioids only for medicinal use

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10
Q

EXPLAIN

The Elimination of Opioids

A

the Half life varies
* morphine 2-3 hours
* Heroin 2-3 mins
* methadone 30 hours

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11
Q

EPLAIN

The Opioid Receptors

A
  • μ
  • 𝛿
  • κ
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12
Q

EPLAIN

GIRK

A

Inwardly rectifying K channel that maintain resting potential

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13
Q

EXPLAIN

what is the most common opioid receptor

A

μ receptor

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14
Q

EXPLAIN

Pure vs Partial opioid receptor agonists

A

pure(Fent Morphine) is more efficent then partial(buprenorphine)

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15
Q

EXPLAIN

Pure vs Mixed opioid receptor antagonists

A

pure (Naloxone/Naltrexone) block receptors and Mixed combine agonist with antagonist

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16
Q

EXPLAIN

Nociception

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A

communication of pain in the nervous system

17
Q

EXPLAIN

Opioids negitive effects on the body

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A

inhibits Respiratiom, cardiovascular function, digestion and suppressed immune responce

18
Q

EXPLAIN

Conditioned Place Preference

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A

u wanna get high because u got high there before

19
Q

EXPLAIN

Effcts opieid Overdoses

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A

severe respiratory depressiom

20
Q

EXPLAIN

Who is Siegel?

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A

he got rat addicted to heroin

21
Q

EXPLAIN

Detocification from opioids

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A

uses a antagonist to reduce systems needing more treatment depending on how long the detox is

PSYCH2800: Drugs & Behaviour (13 decks)

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