Chapter 11 Flashcards
(22 cards)
DEFINE
Cannabis
A family of plants that contain naturally occuring psychoactive cannaboids
LIST
What are the 3 varieties of cannabis?
- Cannabis Sativa
- Cannabis Indica
- Cannabis Ruderalis
NAME
What is the key psychoactive molecule in cannabis?
9-Tetrahydrocannabinol
DEFINE
Marijuana
dried flowers, leaves and stems that are compressed and rolled for smoking
DEFINE
Hashish
Concentrated resin; has higher levels of THC
LIST
What are some synthetic Cannabinoids?
- WIN52212-2
- JWH-018
- JWH-073
EXPLAIN
What is the controlled substance schedule of cannabis in the US?
Schedule I
at a federal level
EXPLAIN
What is Bill C-45?
Canadian law that made cannabis legal with restrictions and limits
LIST
What are the 2 common methods of cannabis use?
- Inhalation (Vape, joint, pipes)
- Oral (Edibles + Beverages)
LIST
What is the active metabolite of cannabis?
11-hydroxy-9-THC
EXPLAIN
What is the consumption method of cannabis that results in higher levels of the active metabolite, 11-hydroxy-9-THC?
Oral consumption, like edibles and drinks
EXPLAIN
When is THC at peak concentration in the fat?
4-5 days after use
DEFINE
What is an endocannabinoid?
Endogenous neurotransmitters that act on the cannabinoid receptors
LIST
What are 2 endocannabinoids?
- Anandamide
- 2-Arachidonoylglycerol
EXPLAIN
What makes Endocannabinoids unique?
- not storied in vesicles
- Retrograde neurotransmission (synthesized and released by postsynaptic)
EXPLAIN
What are CB1 and CB2?
- G-protein-coupled receptors
- Typically have inhibitory effects on presynaptic neurons
LIST
Where can CB1 receptor be concentrated?
- Nucleus Accumbens
- Cerebellum
- Hippocampus
- Hypothalamus
EXPLAIN
Where are CB2 receptors concentrated?
- Outside of the brain on immune system cells
LIST
What are some acute physiological effects of cannabis?
- Elevation of heart rate
- Hypotension
- Reddening of eyes
- Increased appetite
LIST
What are some congitive effects of cannbis?
- mild memory + cognitive deficits
- Some experience pranoia
- Impaired motor coordination, muscle tone, reaction time
- Amotivational syndrome (detachment, blunted emotion and drives, memory and attention disinterest, passivity, apathy, and a general lack of motivation)
LIST
What are some subjective effects of weed?
- Light headnessess
- Euphoria
- Agitation, anxiety
LIST
What are some medicinal uses of cannabis?
- Cancer (Reduces nausea and vomiting)
- Epilepsy (Reduces frequency of seizures
- Neuropathic Pain (Reduces pain)
- Unhealthy weight loss (Promotes weight gain)
