disease
condition that causes the body to function less effectively, producing specific signs or symptoms
signs
can be observed/measured (eg. rashes, fever, coughing, vomiting)
symptoms
can be described/felt (eg. headaches, fatigue, nausea)
infectious diseases
influenza, pneumonia, covid-19, HIV/AIDS, malaria
non-infectious diseases
asthma, diabetes, osteoporosis, dust allergy
how are infectious disease spread?
typical virus cell
a typical virus has a protein coat with specific receptors/antigens on its surface for attachment, enclosing its genetic material (DNA / RNA). it does not have any cellular structures such as cell membrane, cytoplasm or organelles. it does not grow, move, feed, respire or excrete and reproduces only in living host cells.
typical bacterial cell
a typical bacterial cell has a cell wall, cell membrane, flagella, cytoplasm and ribosomes. a bacterial cell also contains DNA (linear - a single strand of genetic material & plasmids - circular DNA molecules) it does not have a membrane-bound nucleus. some are pathogenic (disease-causing) and some non-pathogenic.
signs and symptoms of influenza and pneumococcal disease
• influenza – caused by the influenza virus
sore throat, chills, runny nose, muscle ache, fatigue, fever, headache, cough
• pneumococcal disease – caused by the bacteria, pneumococcus
shortness of breath, vomiting, photophobia, fever, headache, cough
how are viruses transmitted?
the virus attaches to the host cell via its specific antigens/receptors and injects its viral DNA/ viral genetic material into the host cell. using the host cell’s reproduction mechanism, the virus reproduces and multiplies. these viruses break, or lyse, the cell and spread to other cells to continue the cycle.
reduce transmission of viruses
vaccine and how it works
vaccines contains an agent that resembles a pathogen and prevents infectious diseases by stimulating white blood cells to quickly produce antibodies when the pathogen invades. white blood cells bind to antigens on pathogens and the white blood cell is stimulated to divide. many antibodies are produced by the copies, and those antibodies help to destroy pathogens
antibiotics
drugs to treat bacterial functions, made by microorganisms, used to kill and inhibit growth of bacteria, interferes with growth and metabolic activities of pathogens
antibiotics inhibition of cellular structures
antibiotics cannot work on viruses as they don’t have cell wall, cell membrane or ribsomes
overuse for antibiotics
the overuse of antibiotics will naturally select for bacteria that has become mutated to be resistant to the antibiotic, allowing them to survive, multiply and pass on their resistant genes. the spread of the antibiotic- resistant bacteria to others will allow the pathogen to survive, thus rendering that type of antibiotics to be now ineffective.