Chapter 11-Vasculature Flashcards Preview

Robbins Pathology-Cardio (Chapters 11 and 12) > Chapter 11-Vasculature > Flashcards

Flashcards in Chapter 11-Vasculature Deck (165)
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1

What is the prognosis of gloms tumor aka glomangioma or paraganglioma

Benign

2

How are AAA typical found

Pulsating mass in the abdomen

3

What are the morphological features of the Lines of Zahn indicative of

Typically seen on AAA and are indicative of layers of thrombi

4

Which disease’s pathogenesis is linked to atherosclerosis

-Coronary, cerebral and peripheral vascular diseases

5

What are the immune cells characteristic of Behcet disease

Neutrophilic

6

What is the complication commonly seen as a result of churn-Strauss syndrome

Cardiomyopathy, accounting for 50% of the deaths seen with this syndrome

7

What are the clinical presentations in those with IVC syndrome

LE edema
Distention of the superficial collateral veins of the lower abdomen

8

What is generally occurring in Hyaline arteriolosclerosis

1) Hypertension causing damage of the epithelium in small blood vessels
2) Plasma proteins leaking across the damaged endothelium
3) Increased smooth muscle matrix synthesis resulting in thickening of the wall and narrowing of the lumen

9

What is the common location of a glomus tumor

Distal finger

10

What are the common sites of an angiosarcoma

-Skin
-Soft tissue
-Breast
-Liver

11

Which patients are AAA commonly seen

60 year old males who smoked

12

What is a true aneurysm

Intact, but thin, muscular wall at the site of dilation
Saccular- on one side
Fusiform-both sides

13

Venous thrombosis in the form of thrombophlebitis is commonly seen in which neoplasms

-Mucin producing adenocarcinomas such as lung, pancreas, ovarian

14

What are the vessels most commonly involved in atherosclerosis in descending order

1) Abdominal aorta
2) Coronary arteries
3) Popliteal arteries
4) Internal carotid arteries
5) Circle of Willis

15

Which vasculitis is characterized by:
-Medium and small vessels affected
-Lymphocytes, macros, neutrophils
-Eiosinophils*
-Positive ANCA
-History of atopy and asthma

Chung-Strauss syndome

16

Which vasculitis is characterized by:
-Medium and small arteries affected
-Granulomas*
-Lymphocytes, macros, and neutrophils

Granulamatosis with polyangiitis

17

Which vasculitis condition is characterized by:
-Necrotizing granulomas of the upper and lower respiratory tracts
-Necrotizing or granulomatous vasculitis of the respiratory tract
-Focal necrotizing, crescentic glomerulonephritis

Granulomatous is with polyangiitis aka Wegener Granulomatosis

18

Which factors are involved in the inflammation process smooth muscle proliferation and matrix deposition in atherosclerosis

-PDGF
-FGF
-TGF-alpha

19

Which patients are aortic dissections commonly seen

Hypertensive males between 40-60

20

What is the outcome in patients with untreated hypertension

50% die of ischemic heart disease or CHF
30% die of stroke

21

What are the complications seen with Behcet disease

-Neurological involvement
-Rupture of aneurysms

22

What is the prognosis of lymphagiomas

Benign

23

What is the pathogenesis of superior vena cava syndrome

Neoplasms compress or invade the superior vena cava, resulting in the dilation of veins in the neck, head, and arms, along with cyanosis

24

What is a false aneurysm

Defect through the wall fo the vessel that communicated with an extravascular hematoma

25

What the mechanism of pathogenesis in Marfans

1) Results in the decreased synthesis of fibrillin
2) Decreased fibrillin results in decreased TGF-Beta activity
3) Decreased activity results in weakened walls

26

Which vasculitis is characterized by:
-Small arteries, capillaries, and veins
-May or may not contain immune cels

Leukocytociastic vasculitis

27

What are the common complications seen as a result of Kawasaki disease

Aneurysms, leading to thrombosis/rupture, causing an acute MI

28

Which cells are primarily recruited in the inflammation of atherosclerosis

Macrophages and T cells

29

Which conditions can be caused by tertiary syphilis

-Thoracic aorta aneurysms
-Aortic valve annulus aka regurgitation

30

Granulomatosis with polyangiits lesions are characterized by what

-Geographic patterns of central necrosis, usually in the upper respiratory tract
-Cavitation lesions and necrotizing granulomas in the lower tract