Chapter 12 lecture 2 soft tissue tumors Flashcards

1
Q

What is a true neoplasm exhibiting fibroblastic and histiocytic differentiation?

A

-Fibrous histiocytoma

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2
Q

Where does fibrous histiocytoma most commonly occur?

A

-Skin

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3
Q

What is a fibrous histiocytoma on the skin known as?

A

-Dermatofibroma

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4
Q

What represents the oral counterpart of cutaneous focal mucinosis?

A

-Oral focal mucinosis

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5
Q

What does oral focal mucinosis result from?

A

-Overproduction of hyaluronic acid by fibroblasts

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6
Q

Who does oral focal mucinosis most commonly occur in?

A

-Young females

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7
Q

Where does oral focal mucinosis tend to occur?

A
  • gingiva 2/3

- hard palate 1/3

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8
Q

What is not a true granuloma but is a reactive lesion to local irritation or trauma?

A

-Pyogenic granuloma

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9
Q

Where is the location that you can see a pyogenic granuloma?

A
  • Gingiva
  • Lips
  • Tongue
  • Buccal mucosa
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10
Q

Who is pyogenic granulomas most commonly found in?

A
  • Children

- Young adults

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11
Q

What is pyogenic granuloma also known as?

A
  • Pregnancy tumor

- Granuloma gravidarum

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12
Q

When you excise a pyogenic granuloma how far should you go?

A

-The excision should extend to periosteum

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13
Q

Besides pyogenic granuloma what is another granuloma that is a reactive lesion caused by local irritation or trauma?

A

-Peripheral Giant Cell Granuloma

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14
Q

Where does the peripheral Giant cell granuloma occur exclusively?

A

-On the gingiva or edentulous alveolar ridge

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15
Q

How do you differentiate a Pyogenic granuloma from a PGCG?

A

-The PGCG is more blue or purple compared to the bright red of a PG

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16
Q

What is the treatment for a pyogenic giant cell granuloma?

A

-local surgical excision down to underlying bone

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17
Q

What can pyogenic giant cell granulomas due to the bone?

A

-Produce a cupping resorption of the underlying alveolar bone

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18
Q

What are four differentials that you use if you see a bump on the gums?

A
  • IFH (inflammatory fibrous hyperplasia)
  • Pyogenic granuloma (vasculature)
  • Pyogenic giant cell granuloma (giant cells)
  • Peripheral Ossifying Fibroma (bone)
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19
Q

Where does a peripheral ossifying Fibroma occur exclusively?

20
Q

Where does a peripheral ossifying fibroma originate from?

A

-Dental papilla

21
Q

Where do 50% of peripheral ossifying fibromas occur?

A

-Incisor cuspid region

22
Q

What is a benign tumor of fat?

23
Q

What is the most common mesenchymal neoplasm?

24
Q

T/F A Peripheral ossifying fibroma can occur on the mucosa

A

False

-It can only occur on the gingiva

25
What is the average age of a person with a peripheral ossifying fibroma?
-15
26
What does a peripheral ossifying fibroma appear as clinically most of the time?
-Pale bump on the gums
27
What does a lipoma do in formalin?
-Float
28
What is a neuroma?
-Benign tumor of nerve tissue
29
What can a neuroma be?
- A traumatic neuroma | - Palisaded encapsulated neuroma
30
What is the most common area of a neuroma?
-Mental foramen area
31
What is a palisaded encapsulated neuroma also known as?
-Solitary circumscribed neuroma
32
What is a benign neural neoplasm of Schwann cell origin?
-Schwannoma (Neurilemoma)
33
What are characteristics of a Shwannoma?
- Slow-growing - Encapsulated - Associated with the nerve trung
34
Who do Shwannomas most commonly occur in?
-Middle-aged adults
35
What is the most common location for an oral Shwanoma?
-Tongue
36
What are the histopathologic feature of a Shwannoma?
- Antoni A | - Antoni B
37
What do Antoni A bodies have associated with them?
- Verocay bodies
38
What do Antoni B bodies have with them?
-Everything that is not is not Antoni A
39
What is the most common type of peripheral nerve neoplasm?
-Neurofibroma
40
What can arise as solitary tumors or be a component of neurofibromatosis?
-Neurofibroma
41
What is neurofibromatosis type I also known as?
-Recklinghausen's disease of the skin
42
What is a pathognomonic of NF1?
-Plexiform varient
43
What are the diagnostic criteria of NF1? (need 2 or more)
- Six or more cafe au lait macules - Two or more Neurofibromas or one plexiform Neurofibromas - Freckling in the axillary region (Crowe's sign) - Optic glioma - Two or more iris hamartomas (Lisch nodules) - Osseous lesion such as sphenoid dysplasia - First degree relative with NF1
44
What is crowe's sign?
-Freckling in the axillary region
45
What does a plexiform neurofibromatotis feel like?
Bag of worms
46
What are the oral manifestations that can be seen with NF1?
- Enlargment of the fungiform papilla - Intraoral neurofibromas - Enlargment of the mandibular foramen or canal
47
What is a lisch nodule?
-Two or more iris hamartomas